1983
Histopathologic and ultrastructural studies of disseminated cytomegalovirus infection in strain 2 guinea pigs.
Fong C, Lucia H, Bia F, Hsiung G. Histopathologic and ultrastructural studies of disseminated cytomegalovirus infection in strain 2 guinea pigs. Laboratory Investigation 1983, 49: 183-94. PMID: 6308346.Peer-Reviewed Original ResearchConceptsStrain 2 guinea pigsGuinea pigsCytomegalovirus infectionSalivary glandsViral inclusionsCultured guinea pig cellsGuinea pig cytomegalovirus infectionDisseminated cytomegalovirus infectionSevere disseminated diseaseHigh mortality rateUseful animal modelGland duct cellsSalivary gland duct cellsDisseminated diseaseGuinea pig cellsHistologic examinationElectron microscopic examinationAnimal modelsMortality rateVirus inoculationGross lesionsInfectious virusVisceral tissuesPig cellsIntranuclear inclusions
1981
Cytomegalovirus-induced mononucleosis in guinea pigs
Griffith B, Lucia H, Bia F, Hsiung G. Cytomegalovirus-induced mononucleosis in guinea pigs. Infection And Immunity 1981, 32: 857-863. PMID: 6265366, PMCID: PMC351522, DOI: 10.1128/iai.32.2.857-863.1981.Peer-Reviewed Original ResearchConceptsGuinea pigsAcute infectionLymphoid tissueBone marrowB-lymphocyte-enriched populationsTransient hematological changesB-cell areasCMV mononucleosisAtypical lymphocytesCMV infectionCytomegalovirus infectionLymph nodesBlood countMononuclear cellsChronic infectionSpleen sizeHematological changesSplenic macrophagesVirus persistenceVirus inoculationInfectionBlood parametersVirus distributionMononucleosisSpleen