1986
Effects of Cyclosporine and Cortisone on the Pathogenesis of Primary Infection with Cytomegalovirus in the Guinea Pig
MacGregor M, Lucia H, Vine W, FitzGerald P, Bia F. Effects of Cyclosporine and Cortisone on the Pathogenesis of Primary Infection with Cytomegalovirus in the Guinea Pig. The Journal Of Infectious Diseases 1986, 153: 503-510. PMID: 3005426, DOI: 10.1093/infdis/153.3.503.Peer-Reviewed Original ResearchConceptsPrimary infectionGuinea pigsTissue culture infectious dosesEffect of cyclosporineGuinea pig modelRate of isolationGuinea pig cytomegalovirusOral CsAImmunosuppressive agentsInflammatory responseInfectious dosesViral inclusionsPig modelDay 14Day 0CortisoneCytomegalovirusMinimal inflammatory responseCsALymphopeniaPathogenesisInfectionUntreated controlsAnimalsTissue
1985
Effects of Cyclosporine on the Pathogenesis of Primary Cytomegalovirus Infection in the Guinea Pig
Bia F, Lucia H, Bia M, Vine W, Tuttle A. Effects of Cyclosporine on the Pathogenesis of Primary Cytomegalovirus Infection in the Guinea Pig. Intervirology 1985, 24: 154-165. PMID: 2999030, DOI: 10.1159/000149635.Peer-Reviewed Original ResearchConceptsPrimary cytomegalovirus infectionGuinea pigsCytomegalovirus infectionPrimary CMV infectionEffect of cyclosporinePresence of CMVGuinea pig CMVGuinea pig modelInternal organsHartley guinea pigsTotal body weightUntreated controlsCMV isolationOral CsACMV infectionCsA administrationLymphocyte valuesLymphocytes/Inflammatory responseMean changeViral inclusionsBody weightPig modelDay 0CMV
1984
Vaccination Against Transplacental Cytomegalovirus Transmission: Vaccine Reactivation and Efficacy in Guinea Pigs
Bia F, Miller S, Lucia H, Griffith B, Tarsio M, Hsiung G. Vaccination Against Transplacental Cytomegalovirus Transmission: Vaccine Reactivation and Efficacy in Guinea Pigs. The Journal Of Infectious Diseases 1984, 149: 355-362. PMID: 6325549, DOI: 10.1093/infdis/149.3.355.Peer-Reviewed Original ResearchConceptsCMV infectionSubsequent pregnancyThroat swabsCMV transmissionGuinea pigsNonpregnant control animalsCongenital CMV infectionTissue culture infective dosesHartley strain guinea pigsGuinea pig modelCMV vaccineCytomegalovirus transmissionCytomegalovirus infectionFetal infectionPregnant controlsAcute viremiaGeneralized infectionCytomegalovirus vaccineControl animalsInfective dosesPregnancyPregnant animalsVaccineInfectionSwabs
1983
Cytomegaloviral Infections in the Guinea Pig: Experimental Models for Human Disease
Bia F, Griffith B, Fong C, Hsiung G. Cytomegaloviral Infections in the Guinea Pig: Experimental Models for Human Disease. Clinical Infectious Diseases 1983, 5: 177-195. PMID: 6302812, DOI: 10.1093/clinids/5.2.177.Peer-Reviewed Original ResearchConceptsGuinea pig cytomegalovirusInterstitial pneumoniaTransplacental transmissionGuinea pigsPrimary CMV infectionPolymorphonuclear leukocyte functionGuinea pig modelSalivary gland virusHuman viral infectionsCongenital infectionCytomegaloviral infectionCMV infectionBlood transfusionFungal superinfectionsViremic infectionAntigen vaccineTransmission of virusesSuch vaccinesLeukocyte functionHuman diseasesCocultivation techniquesViral infectionPig modelCytomegalovirusInfectious diseases