1988
Subsets of GABAergic neurons in dissociated cell cultures of neonatal rat cerebral cortex show co-localization with specific modulator peptides.
Alho H, Ferrarese C, Vicini S, Vaccarino F. Subsets of GABAergic neurons in dissociated cell cultures of neonatal rat cerebral cortex show co-localization with specific modulator peptides. Brain Research 1988, 467: 193-204. PMID: 3378169, DOI: 10.1016/0165-3806(88)90023-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornCarrier ProteinsCells, CulturedCerebral CortexDiazepam Binding InhibitorElectrophysiologyGABA Plasma Membrane Transport ProteinsGamma-Aminobutyric AcidGlutamate DecarboxylaseMembrane ProteinsMembrane Transport ProteinsNerve Tissue ProteinsNeuronsNeuropeptidesOrganic Anion TransportersPeptide FragmentsRatsConceptsGlutamic acid decarboxylaseNeuropeptide YGABAergic propertiesCerebral cortexGAD immunoreactivityGABA-modulinNeonatal cortical neuronsPrimary culturesInhibitory synaptic currentsDouble-labeling studiesBenzodiazepine recognition sitesGABA receptor modulatorsUseful experimental modelDays of cultureNeuroregulatory peptideGABAergic neuronsGABAergic neurotransmissionSpontaneous excitatoryNeonatal ratsCortical neuronsReceptor modulatorsLower incidenceTyrosine hydroxylaseSynaptic currentsCultured neurons
1985
GABA‐Modulin: A Synaptosomal Basic Protein that Differs from Small Myelin Basic Protein of Rat Brain
Vaccarino F, Tronconi B, Panula P, Guidotti A, Costa E. GABA‐Modulin: A Synaptosomal Basic Protein that Differs from Small Myelin Basic Protein of Rat Brain. Journal Of Neurochemistry 1985, 44: 278-290. PMID: 3964832, DOI: 10.1111/j.1471-4159.1985.tb07142.x.Peer-Reviewed Original ResearchMeSH KeywordsAmino AcidsAnimalsBrain ChemistryCarrier ProteinsChromatography, High Pressure LiquidCyanogen BromideGABA Plasma Membrane Transport ProteinsMembrane ProteinsMembrane Transport ProteinsMuscimolMyelin ProteinsMyelin SheathNerve Tissue ProteinsOrganic Anion TransportersPeptide FragmentsRatsSubcellular FractionsSynaptosomesTissue DistributionConceptsGABA-modulinSmall myelin basic proteinMyelin basic proteinRat brainBasic proteinModulation of GABANeuronal membrane functionNeurotransmitter receptorsSynaptosomal fractionGABA bindingSynaptic membranesSynaptosomal membranesStaphylococcal V8 protease digestionSynaptosomal proteinsNeuronal specificityAcid compositionHigh potencyGABAHigh-affinity bindingBrainMyelinAmino acid compositionTotal synaptosomal proteinApparent molecular weightMembrane function