2020
Stiripentol fails to lower plasma oxalate in a dialysis-dependent PH1 patient
Kempf C, Pfau A, Holle J, Müller-Schlüter K, Bufler P, Knauf F, Müller D. Stiripentol fails to lower plasma oxalate in a dialysis-dependent PH1 patient. Pediatric Nephrology 2020, 35: 1787-1789. PMID: 32418144, PMCID: PMC7385015, DOI: 10.1007/s00467-020-04585-5.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseChronic kidney diseaseLactate dehydrogenase 5Urinary oxalateAdvanced chronic kidney diseaseAnti-convulsive drugsMultisystemic metabolic disorderLiver-kidney transplantationMajority of patientsCurrent standard treatmentTreatment of childrenHyperoxaluria type 1Anuric infantsPH patientsUox excretionRenal diseaseDravet syndromeKidney diseasePrimary hyperoxaluriaCompassionate useStandard treatmentPlasma concentrationsMetabolic disordersPromising drugEarly infancy
2014
Neue Einblicke in die Pathogenese der Nierensteine
Knauf F. Neue Einblicke in die Pathogenese der Nierensteine. Die Nephrologie 2014, 9: 196-203. DOI: 10.1007/s11560-013-0850-0.Peer-Reviewed Original ResearchRenal stone diseaseStone diseaseMajority of patientsMethodsThis review articleNovel therapeutic agentsPathogenesis of nephrolithiasisSelective literature researchUrine volumeRisk factorsUrine collectionUrine pHCalcium stonesTherapeutic approachesMouse modelStone formationInflammasome responseTherapeutic agentsKidney stonesStone analysisUric acidConcentration of calciumPathogenesisDiseaseReview articleChronic problems