Molecular Basis of Branched Peptides Resistance to Enzyme Proteolysis
Falciani C, Lozzi L, Pini A, Corti F, Fabbrini M, Bernini A, Lelli B, Niccolai N, Bracci L. Molecular Basis of Branched Peptides Resistance to Enzyme Proteolysis. Chemical Biology & Drug Design 2007, 69: 216-221. PMID: 17441908, DOI: 10.1111/j.1747-0285.2007.00487.x.Peer-Reviewed Original ResearchConceptsForm of dendrimersDifferent bioactive peptidesStructure-based hypothesesMass spectrometryUnmodified peptidesMultimeric peptidesProteolytic stabilityBioactive peptidesPressure liquid chromatographyLiquid chromatographyHigh-pressure liquid chromatographyLinear moleculesPeptide copiesEnzyme proteolysisProteolytic resistanceHuman plasmaSame peptideSynthetic peptidesPeptidesDendrimersPeptide resistanceSpectrometryMultimericityChromatographyMolecules