2020
Imaging Appearance of Nongerminoma Pediatric Ovarian Germ Cell Tumors Does Not Discriminate Benign from Malignant Histology
Billmire D, Dicken B, Rescorla F, Ross J, Piao J, Huang L, Krailo M, Pashankar F, Frazier L, Group C. Imaging Appearance of Nongerminoma Pediatric Ovarian Germ Cell Tumors Does Not Discriminate Benign from Malignant Histology. Journal Of Pediatric And Adolescent Gynecology 2020, 34: 383-386. PMID: 33316416, PMCID: PMC8096645, DOI: 10.1016/j.jpag.2020.11.014.Peer-Reviewed Original ResearchConceptsMalignant ovarian germ cell tumorsMalignant germ cell tumorsGerm cell tumorsOvarian germ cell tumorsCell tumorsOncology GroupMalignant histologyImaging appearancesExtracranial malignant germ cell tumorsNonseminomatous malignant germ cell tumorsOvarian malignant germ cell tumorsSolid appearanceComplete surgical stagingElement of teratomaPediatric ovarian neoplasmsPreoperative serum markersChildren's Oncology GroupPrimary ovarian tumorsYolk sac tumorYears of ageAssociated teratomaTeratoma elementsSurgical stagingMixed histologyMulticenter trial
2019
Outcomes of adolescent males with extracranial malignant germ cell tumors compared with children and young adults: A report from the Malignant Germ Cell Tumors International Consortium (MaGIC) group.
Shaikh F, Stark D, Dang H, Xia C, Krailo M, Stenning S, Pashankar F, Rodriguez-Galindo C, Olson T, Hale J, Depani S, Stoneham S, Nicholson J, Murray M, Amatruda J, Billmire D, Fonseca A, Frazier A. Outcomes of adolescent males with extracranial malignant germ cell tumors compared with children and young adults: A report from the Malignant Germ Cell Tumors International Consortium (MaGIC) group. Journal Of Clinical Oncology 2019, 37: 10022-10022. DOI: 10.1200/jco.2019.37.15_suppl.10022.Peer-Reviewed Original ResearchMalignant germ cell tumorsExtracranial malignant germ cell tumorsEvent-free survivalGerm cell tumorsYoung adultsAdolescent patientsCell tumorsCox proportional hazards analysisIndividual patient databaseCox multivariable analysisPlatinum-based chemotherapyProportional hazards analysisYoung adult patientsPediatric cooperative groupsAdult patientsClinical characteristicsSame regimensMale patientsMultivariable analysisInclusion criteriaPatientsPatient databaseAge groupsAdult groupAdolescent males
2017
Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children’s Oncology Group
Shaikh F, Cullen JW, Olson TA, Pashankar F, Malogolowkin MH, Amatruda JF, Villaluna D, Krailo M, Billmire DF, Rescorla FJ, Egler RA, Dicken BJ, Ross JH, Schlatter M, Rodriguez-Galindo C, Frazier AL. Reduced and Compressed Cisplatin-Based Chemotherapy in Children and Adolescents With Intermediate-Risk Extracranial Malignant Germ Cell Tumors: A Report From the Children’s Oncology Group. Journal Of Clinical Oncology 2017, 35: jco.2016.67.654. PMID: 28240974, PMCID: PMC5455599, DOI: 10.1200/jco.2016.67.6544.Peer-Reviewed Original ResearchConceptsMalignant germ cell tumorsEvent-free survivalCycles of PEBEFS ratesGerm cell tumorsOncology GroupCell tumorsExtracranial malignant germ cell tumorsReduction of therapyChildren's Oncology GroupSingle-arm trialLow-stage tumorsHigh-stage tumorsAdministration of cisplatinEligible patientsComparable patientsHistorical cohortPatientsTumorsStatistical significanceComparable childrenPhase 3ChildrenP-valueOne-sided p-value
2016
Reduced and compressed cisplatin-based chemotherapy in children and adolescents with intermediate-risk extracranial malignant germ cell tumors: A report from the Children’s Oncology Group.
Shaikh F, Cullen J, Olson T, Pashankar F, Malogolowkin M, Amatruda J, Villaluna D, Krailo M, Billmire D, Rescorla F, Egler R, Dicken B, Ross J, Schlatter M, Rodriguez-Galindo C, Frazier A. Reduced and compressed cisplatin-based chemotherapy in children and adolescents with intermediate-risk extracranial malignant germ cell tumors: A report from the Children’s Oncology Group. Journal Of Clinical Oncology 2016, 34: 10512-10512. DOI: 10.1200/jco.2016.34.15_suppl.10512.Peer-Reviewed Original ResearchOncology GroupExtracranial malignant germ cell tumorsMalignant germ cell tumorsCisplatin-based chemotherapyChildren's Oncology GroupGerm cell tumorsCell tumorsChemotherapyTumors
2015
Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration
Olson TA, Murray MJ, Rodriguez-Galindo C, Nicholson JC, Billmire DF, Krailo MD, Dang HM, Amatruda JF, Thornton CM, Arul GS, Stoneham SJ, Pashankar F, Stark D, Shaikh F, Gershenson DM, Covens A, Hurteau J, Stenning SP, Feldman DR, Grimison PS, Huddart RA, Sweeney C, Powles T, Lopes LF, dos Santos Agular S, Chinnaswamy G, Khaleel S, Abouelnaga S, Hale JP, Frazier AL. Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration. Journal Of Clinical Oncology 2015, 33: 3018-3028. PMID: 26304902, PMCID: PMC4979195, DOI: 10.1200/jco.2014.60.5337.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetChildCooperative BehaviorDiffusion of InnovationFemaleHistory, 20th CenturyHistory, 21st CenturyHumansInterdisciplinary CommunicationInternational CooperationMaleMedical OncologyNeoplasms, Germ Cell and EmbryonalPediatricsSurvivorsTime FactorsTreatment OutcomeYoung AdultConceptsGerm cell tumorsPrimary tumor siteCell tumorsExtracranial malignant germ cell tumorsExtracranial germ cell tumorsTumor siteMalignant germ cell tumorsSignificant long-term morbidityDifferent risk stratificationLong-term morbidityPlatinum-based chemotherapyPediatric cancer patientsTreatment-related effectsDifferent cooperative groupsCisplatin dosingVariety of specialistsMedical oncologistsGynecologic oncologistsRisk stratificationTherapeutic dilemmaHistologic featuresPediatric oncologistsExcellent outcomesStaging systemCancer patients