2015
A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer
Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR. A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer. New England Journal Of Medicine 2015, 373: 503-510. PMID: 26028131, PMCID: PMC5584380, DOI: 10.1056/nejmoa1504473.Peer-Reviewed Original ResearchConceptsCavity shave marginsPositive marginsPartial mastectomyShave marginsDuctal carcinomaBreast cancerInvasive cancerOutcome measuresStandard partial mastectomySecondary outcome measuresPrimary outcome measureLower ratesRoutine resectionMedian ageClinicopathological characteristicsCavity shavingMargin clearanceSecond surgeryInvasive carcinomaStage 0MastectomyPathological testingPatientsFurther diseaseVolume of tissue
2013
Safety of Sports for Athletes With Implantable Cardioverter-Defibrillators
Lampert R, Olshansky B, Heidbuchel H, Lawless C, Saarel E, Ackerman M, Calkins H, Estes NA, Link MS, Maron BJ, Marcus F, Scheinman M, Wilkoff BL, Zipes DP, Berul CI, Cheng A, Law I, Loomis M, Barth C, Brandt C, Dziura J, Li F, Cannom D. Safety of Sports for Athletes With Implantable Cardioverter-Defibrillators. Circulation 2013, 127: 2021-2030. PMID: 23690453, DOI: 10.1161/circulationaha.112.000447.Peer-Reviewed Original ResearchConceptsPhysical activityImplantable cardioverter defibrillator patientsSafety of sportsCardioverter-defibrillator patientsVentricular arrhythmia episodesImplantable cardioverter defibrillatorSports participationHigh-risk sportsAppropriate shocksMedian ageClinical outcomesVentricular arrhythmiasInformed physicianMedical recordsClinical dataLead malfunctionCardioverter defibrillatorCommon sportsArrhythmia episodesPatient decisionCompetitive athletesPrimary endArrhythmiasICDPhone interviews