2019
Comparison on simultaneous capillary and venous parasite density and genotyping results from children and adults with uncomplicated malaria: a prospective observational study in Uganda
Lehane A, Were M, Wade M, Hamadu M, Cahill M, Kiconco S, Kajubi R, Aweeka F, Mwebaza N, Li F, Parikh S. Comparison on simultaneous capillary and venous parasite density and genotyping results from children and adults with uncomplicated malaria: a prospective observational study in Uganda. BMC Infectious Diseases 2019, 19: 559. PMID: 31242863, PMCID: PMC6595677, DOI: 10.1186/s12879-019-4174-1.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAIDS-Related Opportunistic InfectionsAnimalsAntimalarialsArtemether, Lumefantrine Drug CombinationCapillariesChildChild, PreschoolDrug MonitoringFemaleGenotypeGenotyping TechniquesHIVHIV InfectionsHumansInfantMalaria, FalciparumMaleMiddle AgedParasite LoadParasitemiaPlasmodium falciparumUgandaVeinsYoung AdultConceptsTime of presentationVenous blood smearsProspective observational studyParasite densityVenous compartmentBlood smearsVenous samplesObservational studyMSP-2Uncomplicated Plasmodium falciparum malariaTrial registrationThe trialPlasmodium falciparum malariaResultsTwo hundred twentyMalaria parasite densityClinical research settingResearch settingsUncomplicated malariaArtemether-lumefantrineFalciparum malariaParasite genotypingBland-Altman analysisHundred twentyMalaria diagnosisNew infectionsGold standard method
2016
Parasite Clearance and Artemether Pharmacokinetics Parameters Over the Course of Artemether-Lumefantrine Treatment for Malaria in Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Ugandan Children
Kajubi R, Huang L, Were M, Kiconco S, Li F, Marzan F, Gingrich D, Nyunt MM, Ssebuliba J, Mwebaza N, Aweeka FT, Parikh S. Parasite Clearance and Artemether Pharmacokinetics Parameters Over the Course of Artemether-Lumefantrine Treatment for Malaria in Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Ugandan Children. Open Forum Infectious Diseases 2016, 3: ofw217. PMID: 28018925, PMCID: PMC5170492, DOI: 10.1093/ofid/ofw217.Peer-Reviewed Original ResearchParasite clearanceArtemether-lumefantrineDHA exposureUgandan childrenHuman immunodeficiency virus (HIV) infectionArtemether-lumefantrine treatmentDaily blood smearsEarly parasite clearanceInitial parasite clearanceImmunodeficiency virus infectionLopinavir/ritonavirHuman immunodeficiency virusParasite clearance ratesAL efficacyArtemisinin pharmacokineticsAntiretroviral therapyHIV statusImmunodeficiency virusPK exposureArtemisinin resistanceTreatment outcomesVirus infectionHIVPharmacokinetic parametersBlood smears