Acute Left Ventricular Unloading Reduces Atrial Stretch and Inhibits Atrial Arrhythmias
Ishikawa K, Watanabe S, Lee P, Akar FG, Lee A, Bikou O, Fish K, Kho C, Hajjar RJ. Acute Left Ventricular Unloading Reduces Atrial Stretch and Inhibits Atrial Arrhythmias. Journal Of The American College Of Cardiology 2018, 72: 738-750. PMID: 30092950, PMCID: PMC6160394, DOI: 10.1016/j.jacc.2018.05.059.Peer-Reviewed Original ResearchConceptsLV end-diastolic pressureEnd-diastolic pressureLV unloadingMyocardial infarctionSubacute myocardial infarctionPressure-volume loopsLA pressureAortic regurgitationRyanodine receptor phosphorylationLA tissuesLV loadingReduced LV ejection fractionAtrial arrhythmia inducibilityLV assist deviceLV ejection fractionMean LA pressureLeft ventricular performancePressure-volume catheterMaximum LA volumeLV loading conditionsReceptor phosphorylationMedian 55NOX2 levelsArrhythmia inducibilityAtrial stretch