Molecular Basis of Arrhythmias
Shah M, Akar FG, Tomaselli GF. Molecular Basis of Arrhythmias. Circulation 2005, 112: 2517-2529. PMID: 16230503, DOI: 10.1161/circulationaha.104.494476.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsIon channel subunit genesChannel subunit genesSubunit geneMolecular basisBasic biologySingle gene disordersNew molecular targetsCardiac arrhythmiasCellular basisGene disordersMolecular targetsMolecular pathogenesisPathophysiological conditionsCritical roleCatecholaminergic polymorphic ventricular tachycardiaPrimary electrical diseasePathological remodelingFundamental mechanismsPolymorphic ventricular tachycardiaImportant insightsLong QT syndromeElectrical diseaseVentricular tachycardiaBrugada syndromeGenes