2023
Responsive neurostimulation as a treatment for super-refractory focal status epilepticus: a systematic review and case series.
Ernst L, Raslan A, Wabulya A, Shin H, Cash S, Yang J, Sagi V, King-Stephens D, Damisah E, Ramos A, Hussain B, Toprani S, Brandman D, Shahlaie K, Kanth K, Arain A, Peters A, Rolston J, Berns M, Patel S, Uysal U. Responsive neurostimulation as a treatment for super-refractory focal status epilepticus: a systematic review and case series. Journal Of Neurosurgery 2023, 140: 201-209. PMID: 37329518, DOI: 10.3171/2023.4.jns23367.Peer-Reviewed Original ResearchConceptsSuper-refractory status epilepticusStatus epilepticusCase seriesTreatment optionsCase reportCollection formFocal status epilepticusRetrospective chart reviewSignificant adverse eventsEffective treatment optionResponsive neurostimulation systemUnique clinical scenarioData collection formOptimal stimulation settingsFocal SEAdverse eventsChart reviewLead placementEligibility criteriaResponsive neurostimulationTenth caseTotal casesIRB approvalStimulation settingsClinical scenarios
2022
Factors Predicting Outcome After Intracranial EEG Evaluation in Patients With Medically Refractory Epilepsy
Sivaraju A, Hirsch L, Gaspard N, Farooque P, Gerrard J, Xu Y, Deng Y, Damisah E, Blumenfeld H, Spencer DD. Factors Predicting Outcome After Intracranial EEG Evaluation in Patients With Medically Refractory Epilepsy. Neurology 2022, 99: e1-e10. PMID: 35508395, PMCID: PMC9259091, DOI: 10.1212/wnl.0000000000200569.Peer-Reviewed Original ResearchConceptsTemporal lobe onsetSeizure freedomResective surgeryIndependent predictorsLesional MRIUnfavorable predictorRefractory epilepsyContinued medical treatmentEpilepsy surgical evaluationFactors Predicting OutcomeIntracranial EEG evaluationNonlesional extratemporal epilepsySubsequent seizure freedomSustained seizure freedomThorough presurgical evaluationSeizure-free outcomeClass II evidenceMedically Refractory EpilepsyRetrospective chart reviewKaplan-Meier curvesSelect clinical scenariosMultivariable regression analysisBest multivariable modelIntracranial EEGSeizure onset localizationOptimizing the surgical management of MRI‐negative epilepsy in the neuromodulation era
McGrath H, Mandel M, Sandhu MRS, Lamsam L, Adenu‐Mensah N, Farooque P, Spencer DD, Damisah EC. Optimizing the surgical management of MRI‐negative epilepsy in the neuromodulation era. Epilepsia Open 2022, 7: 151-159. PMID: 35038792, PMCID: PMC8886105, DOI: 10.1002/epi4.12578.Peer-Reviewed Original ResearchConceptsDeep brain stimulationMRI-negative epilepsyInvasive monitoringResponsive neurostimulationBrain stimulationSeizure outcomeNerve stimulationMRI-negative focal epilepsyGood seizure outcomeLaser interstitial thermal therapyRetrospective chart reviewVagal nerve stimulationVagus nerve stimulationIntracranial electroencephalography monitoringClass 1Interstitial thermal therapyUnderwent resectionChart reviewMore patientsSurgical treatmentAppropriate therapySurgical managementPoor outcomeSurgical interventionSurgical outcomes