2007
Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c‐myc inhibition
Crichlow GV, Zhou H, Hsiao HH, Frederick KB, Debrosse M, Yang Y, Folta-Stogniew EJ, Chung HJ, Fan C, De La Cruz EM, Levens D, Lolis E, Braddock D. Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c‐myc inhibition. The EMBO Journal 2007, 27: 277-289. PMID: 18059478, PMCID: PMC2206118, DOI: 10.1038/sj.emboj.7601936.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsCrystallography, X-RayDimerizationDNADNA HelicasesDNA-Binding ProteinsDrosophila ProteinsGene Expression RegulationHumansMagnetic Resonance SpectroscopyMolecular Sequence DataPromoter Regions, GeneticProtein BindingProto-Oncogene Proteins c-mycRepressor ProteinsRNA Splicing FactorsRNA-Binding ProteinsTranscription Factor TFIIHConceptsRRM domainDNA bindingFirst RRM domainSecond RRM domainC-myc transcriptional controlSite-directed mutationsDNA upstreamTranscriptional controlInfluences transcriptionC-Myc inhibitionNucleic acid recognitionPromoter sitesP1 promoterAnalogous mutationCell homeostasisC-MycTFIIHProteinLight scattering revealBinding sitesDNATranscriptionSingle strandsMutationsSize exclusion chromatography
1996
Base-Catalysis of Imino Proton Exchange in DNA: Effects of Catalyst upon DNA Structure and Dynamics
Folta-Stogniew E, Russu I. Base-Catalysis of Imino Proton Exchange in DNA: Effects of Catalyst upon DNA Structure and Dynamics. Biochemistry 1996, 35: 8439-8449. PMID: 8679602, DOI: 10.1021/bi952932z.Peer-Reviewed Original ResearchMeSH KeywordsAlkaliesAmmoniaBase SequenceCatalysisDNAIminesKineticsMagnetic Resonance SpectroscopyModels, ChemicalMolecular Sequence DataNucleic Acid ConformationOligodeoxyribonucleotidesProtonsSolutionsThermodynamicsConceptsDNA dodecamerProton exchangeExchange catalystImino proton exchangeDQF-COSY experimentsImino protonsEffect of catalystNon-exchangeable protonsSelf-complementary DNA dodecamerNucleic acid moleculesNMR spectroscopyDNA structureOverall correlation timeAcid moleculesSolution conformationBase catalysisCatalystProton resonancesWater protonsProton relaxationRate of exchangeNucleic acidsProtonsDodecamerCorrelation time
1995
Energetics of base pair opening in a DNA dodecamer containing an A 3 T 3 tract
Moe J, Folta-Stogniew E, Russu I. Energetics of base pair opening in a DNA dodecamer containing an A 3 T 3 tract. Nucleic Acids Research 1995, 23: 1984-1989. PMID: 7596827, PMCID: PMC306973, DOI: 10.1093/nar/23.11.1984.Peer-Reviewed Original ResearchBase CompositionBase SequenceDNAKineticsMagnetic Resonance SpectroscopyMolecular Sequence DataMolecular StructureTemperature
1994
Sequence dependence of base-pair opening in a DNA dodecamer containing the CACA/GTGT sequence motif.
Folta-Stogniew E, Russu I. Sequence dependence of base-pair opening in a DNA dodecamer containing the CACA/GTGT sequence motif. Biochemistry 1994, 33: 11016-24. PMID: 8086418, DOI: 10.1021/bi00202a022.Peer-Reviewed Original ResearchBase CompositionBase SequenceDNAKineticsMagnetic Resonance SpectroscopyMolecular Sequence DataNucleic Acid ConformationSolutionsThermodynamics