2021
D Radiotranscriptomic analysis of perivascular adipose tissue quantifies vascular inflammation in covid-19 from routine CT angiograms: Stratification of “new UK variant” Infection and prediction of in-hospital outcomes
Kotanidis C, Xie C, Adlam D, Rodrigues J, Siddique M, Lockstone H, Thomas S, Kotronias R, Oikonomou E, Lumley S, Neubauer S, Newby D, Channon K, Deanfield J, Antoniades C. D Radiotranscriptomic analysis of perivascular adipose tissue quantifies vascular inflammation in covid-19 from routine CT angiograms: Stratification of “new UK variant” Infection and prediction of in-hospital outcomes. Heart 2021, 107: a177-a178. DOI: 10.1136/heartjnl-2021-bcs.238.Peer-Reviewed Original ResearchCT pulmonary angiogramComputed tomography angiographyHigher vascular inflammationVascular inflammationCOVID-19 infectionHospital mortalityPrognostic valueCOVID-19Acute COVID-19 infectionExternal testing cohortAnti-inflammatory treatmentInternal mammary arteryPerivascular adipose tissueCOVID-19 patientsVascular inflammatory responseUK variantSARS-CoV-2Novel imaging biomarkersHospital outcomesMammary arteryPulmonary angiogramArterial inflammationHazard ratioClinical factorsRisk stratification
2019
Cardiac Computed Tomography
Oikonomou EK, West HW, Antoniades C. Cardiac Computed Tomography. Arteriosclerosis Thrombosis And Vascular Biology 2019, 39: 2207-2219. PMID: 31510795, DOI: 10.1161/atvbaha.119.312899.Peer-Reviewed Original ResearchConceptsCardiac computed tomographyComputed tomographyCoronary atherosclerosisCoronary plaque burdenAcute coronary syndromeCoronary artery diseaseFirst-line diagnostic testUnstable coronary plaquesMorphological plaque featuresCoronary syndromeInflammatory burdenArterial inflammationArtery diseaseCoronary lesionsPlaque burdenPlaque featuresPrognostic implicationsCoronary plaquesPerivascular fatHemodynamic significanceVulnerable plaquesDiagnostic testsMajor causeTomographyCurrent role