All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors
Gordon K, Manhapra A, Crystal S, Dziura J, Edelman E, Skanderson M, Kerns R, Justice A, Tate J, Becker W. All-cause mortality among males living with and without HIV initiating long-term opioid therapy, and its association with opioid dose, opioid interruption and other factors. Drug And Alcohol Dependence 2020, 216: 108291. PMID: 33011662, PMCID: PMC7644145, DOI: 10.1016/j.drugalcdep.2020.108291.Peer-Reviewed Original ResearchConceptsMorphine equivalent daily doseCause mortalityLong-term opioid therapyTime-updated Cox regressionStrong dose-response relationshipUnnatural deathsEquivalent daily doseDose-response relationshipOpioid doseOpioid therapyUninfected patientsOpioid useDaily doseCox regressionMortality outcomesTherapy doseHigh doseMale veteransOverdose fatalitiesOverdose mortalityPLWHMortalityHIVPatientsDoseOpioid Overdose Prevention Education for Medical Students: Adopting Harm Reduction into Mandatory Clerkship Curricula
Oldfield BJ, Tetrault JM, Wilkins KM, Edelman EJ, Capurso NA. Opioid Overdose Prevention Education for Medical Students: Adopting Harm Reduction into Mandatory Clerkship Curricula. Substance Abuse 2020, 41: 29-34. PMID: 31211657, DOI: 10.1080/08897077.2019.1621241.Peer-Reviewed Original ResearchConceptsHarm reduction theoryOpioid overdosesOverdose educationOpioid overdose prevention educationHarm reductionEducational interventionLow knowledgeOverdose prevention educationOpioid overdose deathsNaloxone distribution programsPublic health crisisOpioid useMedical studentsOverdose deathsOverdose preventionOverdosesModerate improvementPrevention educationNaloxoneClerkship medical studentsHealth crisisDistribution programWeeksInterventionStudents' knowledge