2023
Depression in mothers at childhood: Direct and indirect association with problematic gaming in late adolescence/young adulthood
Roza T, Rabelo-da-Ponte F, Spritzer D, Hoffmann M, Massuda R, Salum G, Miguel E, Rohde L, Pan P, Kessler F, Gadelha A, Passos I. Depression in mothers at childhood: Direct and indirect association with problematic gaming in late adolescence/young adulthood. Journal Of Psychiatric Research 2023, 159: 14-21. PMID: 36652752, DOI: 10.1016/j.jpsychires.2023.01.022.Peer-Reviewed Original ResearchConceptsAdolescence/young adulthoodMothers' depressionLate adolescence/young adulthoodRisk factorsSchool-based cohortYoung adulthoodMultiple confounding factorsLogistic regression modelsInverse probability weightsConfounding factorsExternalizing disordersInternalizing disordersDepressionPotential roleDisordersChildhoodMediatorsRegression modelsMothersSexAdulthoodInternalizing psychopathologySignificant mediatorMediation analysisAssociation
2022
Maternal distress, DNA methylation, and fetal programing of stress physiology in Brazilian mother–infant pairs
Wiley K, Camilo C, Gouveia G, Euclydes V, Panter‐Brick C, Matijasevich A, Ferraro A, Fracolli L, Chiesa A, Miguel E, Polanczyk G, Brentani H. Maternal distress, DNA methylation, and fetal programing of stress physiology in Brazilian mother–infant pairs. Developmental Psychobiology 2022, 65: e22352. PMID: 36567654, PMCID: PMC9792831, DOI: 10.1002/dev.22352.Peer-Reviewed Original ResearchConceptsPrenatal psychological distressLate pregnancyMaternal prenatal psychosocial stressMaternal hair cortisolMaternal prenatal psychological distressPrenatal psychosocial stressPsychological distressAdrenal axis functionInfants of mothersEvening salivary cortisolMother-infant pairsInfant DNA methylationMultivariable linear regressionHair cortisol concentrationsElevated anxiety symptomsAxis functionFetal programingEvening cortisolPregnant adolescentsMaternal distressPsychosocial stressCortisol concentrationsPregnancyHair cortisolSalivary cortisolDisentangling the influences of parental genetics on offspring's cognition, education, and psychopathology via genetic and phenotypic pathways
Axelrud L, Hoffmann M, Vosberg D, Santoro M, Pan P, Gadelha A, Belangero S, Miguel E, Shin J, Thapar A, Smoller J, Pausova Z, Rohde L, Keller M, Paus T, Salum G. Disentangling the influences of parental genetics on offspring's cognition, education, and psychopathology via genetic and phenotypic pathways. Journal Of Child Psychology And Psychiatry 2022, 64: 408-416. PMID: 36162806, DOI: 10.1111/jcpp.13708.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderPolygenic scoresOffspring cognitionIntergenerational transmissionMultiple mediation modelEducational attainmentBehavioral traitsCognitive measuresExecutive functionGeneral intelligenceHyperactivity disorderMediation modelMultiple mediationCognitive AssessmentCognitionPsychopathologyGenetic influencesParental educationPsychotic symptomsDirect associationParental geneticsAttainmentDiscovery sampleGenetic riskFathersInattention symptoms in early pregnancy predict parenting skills and infant maltreatment during the first year of life
de Oliveira J, Fatori D, Shephard E, Xavier M, Matijasevich A, Ferraro A, Rohde L, Chiesa A, Miguel E, Polanczyk G. Inattention symptoms in early pregnancy predict parenting skills and infant maltreatment during the first year of life. Brazilian Journal Of Psychiatry 2022, 44: 388-400. PMID: 35751597, PMCID: PMC9375657, DOI: 10.47626/1516-4446-2021-2045.Peer-Reviewed Original ResearchConceptsMaternal attention-deficit/hyperactivity disorderAttention-deficit/hyperactivity disorderHyperactivity/impulsivity symptomsInattention symptomsImpulsivity symptomsAdolescent mothersHyperactivity disorderMaternal inattentionInfant maltreatmentEarly intervention programsParenting skillsPoor home environmentInfant developmentIntervention programsInattentionChild maltreatmentMaternal competenceMaltreatmentSkillsHome visit programHome environmentFirst yearInfant's lifeMultilevel linear regression modelsEarly pregnancy
2021
A randomized controlled trial testing the efficacy of a Nurse Home Visiting Program for Pregnant Adolescents
Fatori D, Fonseca Zuccolo P, Shephard E, Brentani H, Matijasevich A, Archanjo Ferraro A, Aparecida Fracolli L, Chiesa AM, Leckman J, Constantino Miguel E, V. Polanczyk G. A randomized controlled trial testing the efficacy of a Nurse Home Visiting Program for Pregnant Adolescents. Scientific Reports 2021, 11: 14432. PMID: 34257407, PMCID: PMC8277870, DOI: 10.1038/s41598-021-93938-7.Peer-Reviewed Original ResearchConceptsWeeks of pregnancyAdolescent mothersNurse Home Visiting ProgramStandardized effect sizeChild's ageHome Visiting ProgramTrajectories of outcomesInfant Development-Third EditionEffect sizeLow-income adolescent mothersChildren's expressive language developmentAnthropometric indicesNurse homeDaily stimulationEndpoint assessmentBayley ScalesPregnant adolescentsVisiting ProgramExpressive language developmentPromising interventionChild developmentIntervention effectsPregnancyPoor urban areasAlpha frequencyPromoting mother‐infant relationships and underlying neural correlates: Results from a randomized controlled trial of a home‐visiting program for adolescent mothers in Brazil
Alarcão FSP, Shephard E, Fatori D, Amável R, Chiesa A, Fracolli L, Matijasevich A, Brentani H, Nelson CA, Leckman J, Miguel EC, Polanczyk GV. Promoting mother‐infant relationships and underlying neural correlates: Results from a randomized controlled trial of a home‐visiting program for adolescent mothers in Brazil. Developmental Science 2021, 24: e13113. PMID: 33844435, PMCID: PMC8596406, DOI: 10.1111/desc.13113.Peer-Reviewed Original ResearchConceptsMother-infant attachmentHome visit programHealthy parent-child relationshipsEarly attachment relationshipsAdolescent mothersParent-child relationshipMother-infant interactionGood social behaviourMother-infant relationshipSocial processingAttachment relationshipsNeural correlatesNc amplitudeMother's faceElectrophysiological correlatesAge 6 monthsHome-visiting interventionInfant developmentSocial behaviorPregnant youthSecondary outcomesMiddle-income countriesFirst trimesterMother's healthIntervention group
2020
Family accommodation mediates the impact of childhood anxiety on functional impairment
Macul Ferreira de Barros P, Polga N, Szejko N, Miguel EC, Leckman JF, Silverman WK, Lebowitz ER. Family accommodation mediates the impact of childhood anxiety on functional impairment. Journal Of Anxiety Disorders 2020, 76: 102318. PMID: 33011554, PMCID: PMC7680363, DOI: 10.1016/j.janxdis.2020.102318.Peer-Reviewed Original ResearchMaternal Parenting Electronic Diary in the Context of a Home Visit Intervention for Adolescent Mothers in an Urban Deprived Area of São Paulo, Brazil: Randomized Controlled Trial
Fatori D, Argeu A, Brentani H, Chiesa A, Fracolli L, Matijasevich A, Miguel E, Polanczyk G. Maternal Parenting Electronic Diary in the Context of a Home Visit Intervention for Adolescent Mothers in an Urban Deprived Area of São Paulo, Brazil: Randomized Controlled Trial. JMIR MHealth And UHealth 2020, 8: e13686. PMID: 32720906, PMCID: PMC7420524, DOI: 10.2196/13686.Peer-Reviewed Original ResearchConceptsWeeks of pregnancyMonths of ageCompliance rateAdolescent mothersNurse homePregnant adolescentsDeprived areasHome-visiting interventionElectronic daily diaryLow-income adolescent mothersMaternal parentingControlled TrialsMiddle-income countriesAdverse outcomesEligibility criteriaUrban deprived areasControl groupPregnancyMaternal parenting behaviorsDaily diariesElectronic diaryMonthsInterventionMothersWeeks
2019
Effects of Maternal Psychopathology and Education Level on Neurocognitive Development in Infants of Adolescent Mothers Living in Poverty in Brazil
Shephard E, Fatori D, Mauro L, de Medeiros Filho M, Hoexter M, Chiesa A, Fracolli L, Brentani H, Ferraro A, Nelson C, Miguel E, Polanczyk G. Effects of Maternal Psychopathology and Education Level on Neurocognitive Development in Infants of Adolescent Mothers Living in Poverty in Brazil. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2019, 4: 925-934. PMID: 31345780, PMCID: PMC6863387, DOI: 10.1016/j.bpsc.2019.05.009.Peer-Reviewed Original ResearchConceptsLow maternal educationMaternal psychopathologyAttention-deficit/hyperactivity disorderMaternal anxietyNeurocognitive developmentInfant neurodevelopmentAdolescent mothersMaternal educationHyperactivity disorderInfant neurocognitive developmentMonths of ageResting-state electroencephalographyCluster-based permutation testingEducation levelOscillatory powerEarly brain developmentMaternal symptomsRisk factorsConnectivity alterationsEarly neurocognitive developmentOscillatory connectivityRelative theta powerFunctional connectivityBrain developmentPilot study
2018
Early vulnerabilities for psychiatric disorders in elementary schoolchildren from four Brazilian regions
Paula C, Mari J, Bordin I, Miguel E, Fortes I, Barroso N, Rohde L, Coutinho E. Early vulnerabilities for psychiatric disorders in elementary schoolchildren from four Brazilian regions. Social Psychiatry And Psychiatric Epidemiology 2018, 53: 477-486. PMID: 29511791, DOI: 10.1007/s00127-018-1503-4.Peer-Reviewed Original Research
2017
Comparability of an ADHD Latent Trait Between Groups: Disentangling True Between-Group Differences From Measurement Problems
Cogo-Moreira H, Lúcio P, Swardfager W, Gadelha A, de Jesus Mari J, Miguel E, Rohde L, Salum G. Comparability of an ADHD Latent Trait Between Groups: Disentangling True Between-Group Differences From Measurement Problems. Journal Of Attention Disorders 2017, 23: 712-720. PMID: 28478691, DOI: 10.1177/1087054717707047.Peer-Reviewed Original Research
2015
Attentional bias to threat in children at-risk for emotional disorders: role of gender and type of maternal emotional disorder
Montagner R, Mogg K, Bradley B, Pine D, Czykiel M, Miguel E, Rohde L, Manfro G, Salum G. Attentional bias to threat in children at-risk for emotional disorders: role of gender and type of maternal emotional disorder. European Child & Adolescent Psychiatry 2015, 25: 735-742. PMID: 26547923, DOI: 10.1007/s00787-015-0792-3.Peer-Reviewed Original ResearchConceptsMaternal emotional disordersEmotional disordersAttention biasHappy face cuesThreat attention biasDot-probe paradigmMood disordersAttention biasesAttentional biasThreat biasThreat biasesNeutral facesEmotion disordersRole of genderLongitudinal researchDepression symptomsGroup differencesDisorder interactionFamilial riskSignificant genderHigh Risk Cohort StudyLarge sampleBiasesAnxietyPsychiatric disorders