2021
Cellular and Extracellular White Matter Abnormalities in Obsessive-Compulsive Disorder: A Diffusion Magnetic Resonance Imaging Study
Maziero M, Seitz-Holland J, Cho K, Goldenberg J, Tanamatis T, Diniz J, Cappi C, Alice de Mathis M, Otaduy M, da Graça Morais Martin M, de Melo Felipe da Silva R, Shavitt R, Batistuzzo M, Lopes A, Miguel E, Pasternak O, Hoexter M. Cellular and Extracellular White Matter Abnormalities in Obsessive-Compulsive Disorder: A Diffusion Magnetic Resonance Imaging Study. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2021, 6: 983-991. PMID: 33862255, PMCID: PMC8502196, DOI: 10.1016/j.bpsc.2021.04.001.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingFemaleHumansMaleMiddle AgedObsessive-Compulsive DisorderWhite MatterYoung AdultConceptsObsessive-compulsive disorderClinical variablesControl subjectsLower fractional anisotropyFractional anisotropyWhite matterDiffusion-weighted magnetic resonance imagingMagnetic resonance imaging studyDiffusion measuresDiffusion magnetic resonance imaging studyWhite matter abnormalitiesTract-based spatial statisticsResonance imaging studyMagnetic resonance imagingFree-water imagingExtracellular abnormalities
2020
Toward identifying reproducible brain signatures of obsessive-compulsive profiles: rationale and methods for a new global initiative
Simpson H, van den Heuvel O, Miguel E, Reddy Y, Stein D, Lewis-Fernández R, Shavitt R, Lochner C, Pouwels P, Narayanawamy J, Venkatasubramanian G, Hezel D, Vriend C, Batistuzzo M, Hoexter M, de Joode N, Costa D, de Mathis M, Sheshachala K, Narayan M, van Balkom A, Batelaan N, Venkataram S, Cherian A, Marincowitz C, Pannekoek N, Stovezky Y, Mare K, Liu F, Otaduy M, Pastorello B, Rao R, Katechis M, Van Meter P, Wall M. Toward identifying reproducible brain signatures of obsessive-compulsive profiles: rationale and methods for a new global initiative. BMC Psychiatry 2020, 20: 68. PMID: 32059696, PMCID: PMC7023814, DOI: 10.1186/s12888-020-2439-2.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingCircuit abnormalitiesNew global initiativesBrain signaturesGlobal InitiativeHealthy control subjectsMedication-free adultsMultiple brain circuitsMedication-free subjectsBackgroundObsessive–compulsive disorderClinical profileClinical symptomsControl subjectsClinical evaluationHealthy controlsLeading causeGlobal disabilityLifetime prevalenceResonance imagingNeurocognitive assessmentBrain circuitsImaging signaturesFunctional connectivityBrain-behavior associationsDisease dimensions
2016
Children with Poor Reading Skills at the Word Level Show Reduced Fractional Anisotropy in White Matter Tracts of Both Hemispheres
de Moura L, Cogo-Moreira H, de Ávila C, Pan P, Gadelha A, Moriyama T, Del Aquilla M, Hoexter M, Salum G, Picon F, Anés M, Mercadante M, Lacerda A, Amaro E, Miguel E, Rohde L, Bressan R, McGuire P, Sato J, de Jesus Mari J, Jackowski A. Children with Poor Reading Skills at the Word Level Show Reduced Fractional Anisotropy in White Matter Tracts of Both Hemispheres. Brain Connectivity 2016, 6: 519-523. PMID: 27353747, DOI: 10.1089/brain.2016.0430.Peer-Reviewed Original ResearchMeSH KeywordsAnisotropyAptitudeAptitude TestsBrainChildDiffusion Tensor ImagingFemaleHumansMaleReadingWhite MatterConceptsWhite matter tractsRadial diffusivityDiffusion tensor imaging studyLatent class analysisSignificant fractional anisotropy reductionYears of ageReduced fractional anisotropyFractional anisotropy reductionsMultiple cortical regionsWhite matter microstructureWhite matterWidespread structural alterationsCortical regionsImaging studiesFractional anisotropyLeft hemisphereTract