Perinatal complications, lipid peroxidation, and mental health problems in a large community pediatric sample
Mansur R, Cunha G, Asevedo E, Zugman A, Rios A, Salum G, Pan P, Gadelha A, Levandowski M, Belangero S, Manfro G, Stertz L, Kauer-Sant’anna M, Miguel E, Bressan R, Mari J, Grassi-Oliveira R, Brietzke E. Perinatal complications, lipid peroxidation, and mental health problems in a large community pediatric sample. European Child & Adolescent Psychiatry 2016, 26: 521-529. PMID: 27785581, DOI: 10.1007/s00787-016-0914-6.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBrazilChecklistChildChild Behavior DisordersCohort StudiesDevelopmental DisabilitiesFemaleHumansLipid PeroxidationLong Term Adverse EffectsMaleMalondialdehydeMental DisordersMental HealthOxidative StressPregnancyPsychopathologySocioeconomic FactorsThiobarbituric Acid Reactive SubstancesConceptsPerinatal complicationsMental health problemsCumulative exposureLipid peroxidationTBARS levelsChild Behavior ChecklistHealth problemsHigh Risk Cohort StudyMini-International Psychiatric InterviewYears of ageCBCL total problemsIndividual cumulative exposureEarly life environmentCohort studyCumulative risk indexSerum levelsPerinatal historyUnexposed groupExploratory mediation analysisPsychiatric interviewComplicationsPsychiatric disordersSocio-economic statusPediatric samplesOxidative stressSocioeconomic Disadvantage Moderates the Association between Peripheral Biomarkers and Childhood Psychopathology
Mansur R, Cunha G, Asevedo E, Zugman A, Zeni-Graiff M, Rios A, Sethi S, Maurya P, Levandowski M, Gadelha A, Pan P, Stertz L, Belangero S, Anna M, Teixeira A, Mari J, Rohde L, Miguel E, McIntyre R, Grassi-Oliveira R, Bressan R, Brietzke E. Socioeconomic Disadvantage Moderates the Association between Peripheral Biomarkers and Childhood Psychopathology. PLOS ONE 2016, 11: e0160455. PMID: 27489945, PMCID: PMC4973983, DOI: 10.1371/journal.pone.0160455.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersBrain-Derived Neurotrophic FactorChildCross-Sectional StudiesFemaleHumansInterleukin-6MaleMental DisordersMental HealthSocioeconomic FactorsStress, PsychologicalThiobarbituric Acid Reactive SubstancesConceptsBrain-derived neurotrophic factorThiobarbituric acid reactive substancesMental health problemsInterleukin-6Serum levelsHealth problemsSocioeconomic disadvantagePeripheral biomarkersSerum biomarkersOxidative stress markersAcid reactive substancesCross-sectional designChild Behavior Checklist DSMNeurotrophic factorHigher socioeconomic disadvantageSocio-demographic characteristicsBiomarker levelsNeurotrophic proteinsDomains of psychopathologyStress markersSpecific SubscaleCumulative risk modelBiomarkersMultiple biological systemsPathological neurodevelopment