2019
Association between spontaneous activity of the default mode network hubs and leukocyte telomere length in late childhood and early adolescence
Rebello K, Moura L, Xavier G, Spindola L, Carvalho C, Hoexter M, Gadelha A, Picon F, Pan P, Zugman A, Grassi-Oliveira R, Brietzke E, Belangero S, Salum G, Rohde L, Miguel E, Bressan R, Jackowski A, Sato J. Association between spontaneous activity of the default mode network hubs and leukocyte telomere length in late childhood and early adolescence. Journal Of Psychosomatic Research 2019, 127: 109864. PMID: 31706071, DOI: 10.1016/j.jpsychores.2019.109864.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBrain MappingChildFemaleHumansLeukocytesMagnetic Resonance ImagingMaleTelomereConceptsAdverse childhood experiencesMedial prefrontal cortexPosterior cingulate cortexDefault mode networkResting-state functional magnetic resonanceEarly life stressBrain's default mode networkFunctional magnetic resonanceBlood samplesSpontaneous activityDefault mode network hubCingulate cortexDMN hubsPsychiatric conditionsFamily environmentLength shorteningPrefrontal cortexMental healthFractional amplitudeLow-frequency fluctuationsMode networkFamily Environment ScaleHypothesis-driven studiesTelomere lengthLate childhood
2018
Effect of male-specific childhood trauma on telomere length
Xavier G, Spindola L, Ota V, Carvalho C, Maurya P, Tempaku P, Moretti P, Mazotti D, Sato J, Brietzke E, Miguel E, Grassi-Oliveira R, Mari J, Bressan R, Gadelha A, Pan P, Belangero S. Effect of male-specific childhood trauma on telomere length. Journal Of Psychiatric Research 2018, 107: 104-109. PMID: 30384090, DOI: 10.1016/j.jpsychires.2018.10.012.Peer-Reviewed Original ResearchConceptsHigh-risk cohortTelomere lengthImportant risk factorCross-sectional studyChild maltreatmentEarly life stressChild Behavior Checklist scoresSchool-based studySerious lifelong consequencesQuantitative polymerase chain reactionHistory of CMPolymerase chain reactionRisk factorsPsychiatric symptomsPsychiatric disordersMultiplex quantitative polymerase chain reactionLifelong consequencesBlood cellsChildhood traumaCM scoreLife stressChain reactionSexBrazilian High-Risk CohortShort telomeres