2013
Can early improvement be an indicator of treatment response in obsessive-compulsive disorder? Implications for early-treatment decision-making
da Conceição Costa D, Shavitt R, Cesar R, Joaquim M, Borcato S, Valério C, Miguel E, Diniz J. Can early improvement be an indicator of treatment response in obsessive-compulsive disorder? Implications for early-treatment decision-making. Journal Of Psychiatric Research 2013, 47: 1700-1707. PMID: 23948637, DOI: 10.1016/j.jpsychires.2013.07.006.Peer-Reviewed Original ResearchConceptsBaseline Y-BOCS scoresSerotonin reuptake inhibitorsEarly improvementTreatment responseY-BOCS scoresBaseline Yale-Brown ObsessiveLogistic regressionAdequate pharmacological treatmentPotential predictive factorsWeeks of treatmentGreater reductionObsessive-compulsive disorder patientsStepwise logistic regressionWarrants further investigationYale-Brown ObsessiveClinical featuresReuptake inhibitorsObsessive-compulsive disorderPharmacological treatmentPredictive factorsMajor depressionDisorder patientsOCD treatment responseCompulsive ScaleWeeks
2011
Association study between genetic monoaminergic polymorphisms and OCD response to clomipramine treatment
Miguita K, Cordeiro Q, Shavitt R, Miguel E, Vallada H. Association study between genetic monoaminergic polymorphisms and OCD response to clomipramine treatment. Arquivos De Neuro-Psiquiatria 2011, 69: 283-287. PMID: 21625751, DOI: 10.1590/s0004-282x2011000300003.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntidepressive Agents, TricyclicClomipramineDopamine Plasma Membrane Transport ProteinsFemaleGene FrequencyGenotypeHumansMaleMutationNorepinephrine Plasma Membrane Transport ProteinsObsessive-Compulsive DisorderPolymorphism, GeneticReceptors, SerotoninSerotonin Plasma Membrane Transport ProteinsYoung Adult