Assessment of Safety and Outcome of Lateral Hypothalamic Deep Brain Stimulation for Obesity in a Small Series of Patients With Prader-Willi Syndrome
Franco R, Fonoff E, Alvarenga P, Alho E, Lopes A, Hoexter M, Batistuzzo M, Paiva R, Taub A, Shavitt R, Miguel E, Teixeira M, Damiani D, Hamani C. Assessment of Safety and Outcome of Lateral Hypothalamic Deep Brain Stimulation for Obesity in a Small Series of Patients With Prader-Willi Syndrome. JAMA Network Open 2018, 1: e185275. PMID: 30646396, PMCID: PMC6324383, DOI: 10.1001/jamanetworkopen.2018.5275.Peer-Reviewed Original ResearchConceptsDeep brain stimulationPrader-Willi syndromeBody mass indexBlood workupMass indexSleep studiesHormonal levelsBrain stimulationBaseline mean body mass indexLow-frequency deep brain stimulationOutcome of DBSHigh-frequency deep brain stimulationLong-term deep brain stimulationHypothalamic deep brain stimulationLong-term DBS treatmentMean body mass indexSimilar psychiatric conditionsPrevious bariatric surgeryMonths of treatmentPrimary outcome measureUse of medicationsLateral hypothalamic areaHospital das ClínicasDeep brain stimulation electrodesAssessment of safety