2016
Prevalence and correlates of electroconvulsive therapy delivery in 1001 obsessive-compulsive disorder outpatients
dos Santos-Ribeiro S, Lins-Martins N, Frydman I, do Rosário M, Ferrão Y, Shavitt R, Yücel M, Miguel E, Fontenelle L. Prevalence and correlates of electroconvulsive therapy delivery in 1001 obsessive-compulsive disorder outpatients. Psychiatry Research 2016, 239: 145-148. PMID: 27137976, DOI: 10.1016/j.psychres.2016.03.020.Peer-Reviewed Original ResearchConceptsElectroconvulsive therapyObsessive-compulsive disorderOCD patientsHigher global severitySerotonin reuptake inhibitorsObsessive-compulsive disorder outpatientsContamination/washing symptomsRates of psychosisDifferent specialized centersAdequate trialReuptake inhibitorsSpecialized centersGlobal severityGreater suicidalityDisorder outpatientsTherapy deliveryTerms of responseAssessment BatteryPatientsOCD symptomsSymptomsWashing symptomsAntipsychoticsOutpatientsTherapy
2014
Gamma Ventral Capsulotomy for Obsessive-Compulsive Disorder: A Randomized Clinical Trial
Lopes A, Greenberg B, Canteras M, Batistuzzo M, Hoexter M, Gentil A, Pereira C, Joaquim M, de Mathis M, D’Alcante C, Taub A, de Castro D, Tokeshi L, Sampaio L, Leite C, Shavitt R, Diniz J, Busatto G, Norén G, Rasmussen S, Miguel E. Gamma Ventral Capsulotomy for Obsessive-Compulsive Disorder: A Randomized Clinical Trial. JAMA Psychiatry 2014, 71: 1066-1076. PMID: 25054836, DOI: 10.1001/jamapsychiatry.2014.1193.Peer-Reviewed Original ResearchConceptsIntractable obsessive-compulsive disorderObsessive-compulsive disorderClinical trialsGamma ventral capsulotomyClinical Global Impressions-Improvement scaleSerious adverse eventsRandomized clinical trialsCGI-I ratingsDeep brain stimulationYale-Brown ObsessiveAdverse eventsMonth 12Additional patientsActive treatmentSham groupSymptom improvementInternal capsuleSpecialized centersNeurosurgical ablationAnterior limbMAIN OUTCOMEPsychiatric disordersPatientsOCD symptom improvementSelect cases