2021
Cellular and Extracellular White Matter Abnormalities in Obsessive-Compulsive Disorder: A Diffusion Magnetic Resonance Imaging Study
Maziero M, Seitz-Holland J, Cho K, Goldenberg J, Tanamatis T, Diniz J, Cappi C, Alice de Mathis M, Otaduy M, da Graça Morais Martin M, de Melo Felipe da Silva R, Shavitt R, Batistuzzo M, Lopes A, Miguel E, Pasternak O, Hoexter M. Cellular and Extracellular White Matter Abnormalities in Obsessive-Compulsive Disorder: A Diffusion Magnetic Resonance Imaging Study. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2021, 6: 983-991. PMID: 33862255, PMCID: PMC8502196, DOI: 10.1016/j.bpsc.2021.04.001.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical variablesControl subjectsLower fractional anisotropyFractional anisotropyWhite matterDiffusion-weighted magnetic resonance imagingMagnetic resonance imaging studyDiffusion measuresDiffusion magnetic resonance imaging studyWhite matter abnormalitiesTract-based spatial statisticsResonance imaging studyMagnetic resonance imagingFree-water imagingExtracellular abnormalities
2005
Regional Gray Matter Abnormalities in Obsessive-Compulsive Disorder: A Voxel-Based Morphometry Study
Valente A, Miguel E, Castro C, Amaro E, Duran F, Buchpiguel C, Chitnis X, McGuire P, Busatto G. Regional Gray Matter Abnormalities in Obsessive-Compulsive Disorder: A Voxel-Based Morphometry Study. Biological Psychiatry 2005, 58: 479-487. PMID: 15978549, DOI: 10.1016/j.biopsych.2005.04.021.Peer-Reviewed Original ResearchConceptsVoxel-based morphometryObsessive-compulsive disorderGray matterLeft anterior cingulate cortexOCD patientsOCD subjectsParietal associative cortexMagnetic resonance imaging studyStructural magnetic resonance imaging (MRI) studiesRegional gray matter abnormalitiesGray matter reductionsGray matter abnormalitiesResonance imaging studyGray matter volumeAnterior cingulate cortexWarrants further investigationTemporolimbic regionsMedial thalamusBrain abnormalitiesObsessive-compulsive symptom severityHealthy volunteersImplicating dysfunctionMatter volumeAssociative cortexMorphometry study