Effect of male-specific childhood trauma on telomere length
Xavier G, Spindola L, Ota V, Carvalho C, Maurya P, Tempaku P, Moretti P, Mazotti D, Sato J, Brietzke E, Miguel E, Grassi-Oliveira R, Mari J, Bressan R, Gadelha A, Pan P, Belangero S. Effect of male-specific childhood trauma on telomere length. Journal Of Psychiatric Research 2018, 107: 104-109. PMID: 30384090, DOI: 10.1016/j.jpsychires.2018.10.012.Peer-Reviewed Original ResearchConceptsHigh-risk cohortTelomere lengthImportant risk factorCross-sectional studyChild maltreatmentEarly life stressChild Behavior Checklist scoresSchool-based studySerious lifelong consequencesQuantitative polymerase chain reactionHistory of CMPolymerase chain reactionRisk factorsPsychiatric symptomsPsychiatric disordersMultiplex quantitative polymerase chain reactionLifelong consequencesBlood cellsChildhood traumaCM scoreLife stressChain reactionSexBrazilian High-Risk CohortShort telomeresObsessive-compulsive symptoms in children with first degree relatives diagnosed with obsessive-compulsive disorder
Chacon P, Bernardes E, Faggian L, Batistuzzo M, Moriyama T, Miguel E, Polanczyk G. Obsessive-compulsive symptoms in children with first degree relatives diagnosed with obsessive-compulsive disorder. Brazilian Journal Of Psychiatry 2018, 40: 388-393. PMID: 29898190, PMCID: PMC6899383, DOI: 10.1590/1516-4446-2017-2321.Peer-Reviewed Original ResearchConceptsPresence of OCSObsessive-compulsive disorderFirst-degree relativesObsessive-compulsive symptomsSocioeconomic statusImportant risk factorLow socioeconomic statusFuture longitudinal studiesClinical correlatesAssessed childrenRisk factorsDegree relativesFamily historySymptomsContamination/Longitudinal studyOCD diagnosisDisordersChildrenHigh rateFamily membersChildhoodCorrelatesStatus