Gamma ventral capsulotomy for treatment of resistant obsessive-compulsive disorder: A structural MRI pilot prospective study
Cecconi J, Lopes A, de Souza Duran F, Santos L, Hoexter M, Gentil A, Canteras M, de Castro C, Norén G, Greenberg B, Rauch S, Busatto G, Miguel E. Gamma ventral capsulotomy for treatment of resistant obsessive-compulsive disorder: A structural MRI pilot prospective study. Neuroscience Letters 2008, 447: 138-142. PMID: 18835422, DOI: 10.1016/j.neulet.2008.09.061.Peer-Reviewed Original ResearchConceptsGamma ventral capsulotomyObsessive-compulsive disorderRefractory obsessive-compulsive disorderResistant obsessive-compulsive disorderRefractory OCD patientsYear of radiosurgeryPilot prospective studyVoxel-based morphometry methodRegional structural abnormalitiesGray matter volumeRight inferior frontal gyrusInferior orbitofrontal cortexPostoperative increaseProspective studyInferior frontal gyrusMagnetic resonance imaging dataMatter volumeMRI scansNeurobiological changesStructural abnormalitiesOrbitofrontal cortexCapsulotomyPatientsOCD patientsFrontal gyrus