2022
Obsessional slowness in obsessive-compulsive disorder: identifying characteristics and comorbidities in a clinical sample
Crowe E, Rosário M, Ferrão Y, Albertella L, Miguel E, Fontenelle L. Obsessional slowness in obsessive-compulsive disorder: identifying characteristics and comorbidities in a clinical sample. International Journal Of Psychiatry In Clinical Practice 2022, 27: 161-170. PMID: 36409661, DOI: 10.1080/13651501.2022.2147441.Peer-Reviewed Original ResearchCo-Occurring Obsessive–Compulsive Disorder and Compulsive Sexual Behavior: Clinical Features and Psychiatric Comorbidities
Snaychuk L, Ferrão Y, Fontenelle L, Miguel E, de Mathis M, Scanavino M, Kim H. Co-Occurring Obsessive–Compulsive Disorder and Compulsive Sexual Behavior: Clinical Features and Psychiatric Comorbidities. Archives Of Sexual Behavior 2022, 51: 4111-4123. PMID: 36066680, DOI: 10.1007/s10508-022-02412-6.Peer-Reviewed Original ResearchConceptsCo-occurring obsessive-compulsive disorderObsessive-compulsive disorderPsychiatric comorbidityCompulsive sexual behaviorBinary logistic regression analysisComorbid obsessive-compulsive disorderGreater psychiatric comorbidityLogistic regression analysisComplex treatment needsSexual behaviorClinical characteristicsClinical factorsClinical featuresStandardized self-report measuresComorbiditiesControl disordersTreatment needsPsychiatric conditionsDisordersRegression analysisPreliminary evidenceSelf-report measuresCurrent studySemi-structured interviewsParticipants
2019
The impact of attention deficit hyperactivity disorder in obsessive‐compulsive disorder subjects
Blanco‐Vieira T, Santos M, Ferrão YA, Torres AR, Miguel EC, Bloch MH, Leckman JF, do Rosario MC. The impact of attention deficit hyperactivity disorder in obsessive‐compulsive disorder subjects. Depression And Anxiety 2019, 36: 533-542. PMID: 30990937, DOI: 10.1002/da.22898.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderAdult OCD patientsObsessive-compulsive disorderDeficit hyperactivity disorderOCD patientsClinical characteristicsExact testFeatures of ADHDHyperactivity disorderSubgroup of patientsAdult obsessive-compulsive disorderComorbid attention deficit hyperactivity disorderSpecific clinical featuresCross-sectional studyObsessive-compulsive disorder (OCD) subjectsLogistic regression analysisFisher's exact testBrazilian Research ConsortiumMann-Whitney testAdult patientsRheumatic feverDevelopment of interventionsClinical featuresObsessive-compulsive spectrum disordersLifetime prevalence
2013
Can early improvement be an indicator of treatment response in obsessive-compulsive disorder? Implications for early-treatment decision-making
da Conceição Costa D, Shavitt R, Cesar R, Joaquim M, Borcato S, Valério C, Miguel E, Diniz J. Can early improvement be an indicator of treatment response in obsessive-compulsive disorder? Implications for early-treatment decision-making. Journal Of Psychiatric Research 2013, 47: 1700-1707. PMID: 23948637, DOI: 10.1016/j.jpsychires.2013.07.006.Peer-Reviewed Original ResearchConceptsBaseline Y-BOCS scoresSerotonin reuptake inhibitorsEarly improvementTreatment responseY-BOCS scoresBaseline Yale-Brown ObsessiveLogistic regressionAdequate pharmacological treatmentPotential predictive factorsWeeks of treatmentGreater reductionObsessive-compulsive disorder patientsStepwise logistic regressionWarrants further investigationYale-Brown ObsessiveClinical featuresReuptake inhibitorsObsessive-compulsive disorderPharmacological treatmentPredictive factorsMajor depressionDisorder patientsOCD treatment responseCompulsive ScaleWeeksClinical features of pure obsessive-compulsive disorder
Torres A, Shavitt R, Torresan R, Ferrão Y, Miguel E, Fontenelle L. Clinical features of pure obsessive-compulsive disorder. Comprehensive Psychiatry 2013, 54: 1042-1052. PMID: 23746710, DOI: 10.1016/j.comppsych.2013.04.013.Peer-Reviewed Original ResearchConceptsPure obsessive-compulsive disorderNon-comorbid patientsObsessive-compulsive disorderYale-Brown ObsessiveClinical characteristicsDSM-IV Axis I DisordersSuicidal thoughtsLogistic regressionCompulsive ScaleOCD patientsAnxious symptomsAxis I comorbidityCross-sectional studyAxis I DisordersStructured Clinical InterviewCo-occurring disordersPrevious suicidal thoughtsBrazilian Research ConsortiumLarge multicenter samplePure OCD patientsAdult patientsClinical featuresLifetime comorbidityPsychiatric comorbidityObsessive-compulsive spectrum disorders
2012
BODY DYSMORPHIC DISORDER IN PATIENTS WITH OBSESSIVE–COMPULSIVE DISORDER: PREVALENCE AND CLINICAL CORRELATES
Costa D, Assunção M, Ferrão Y, Conrado L, Gonzalez C, Fontenelle L, Fossaluza V, Miguel E, Torres A, Shavitt R. BODY DYSMORPHIC DISORDER IN PATIENTS WITH OBSESSIVE–COMPULSIVE DISORDER: PREVALENCE AND CLINICAL CORRELATES. Depression And Anxiety 2012, 29: 966-975. PMID: 22815241, DOI: 10.1002/da.21980.Peer-Reviewed Original ResearchConceptsBody dysmorphic disorderObsessive-compulsive disorderSkin pickingYale-Brown ObsessiveDSM-IV Axis I DisordersClinical Global Impression ScaleEarly onsetCompulsive ScaleOCD patientsDysmorphic disorderGroup of patientsSymptoms of BDDGlobal Impression ScaleAxis I DisordersStructured Clinical InterviewComorbid body dysmorphic disorderBrazilian Research ConsortiumYounger patientsUnemployed patientsClinical featuresObsessive-compulsive spectrum disordersClinical correlatesImpression ScaleChronic depressionClinical assessmentClinical features of tic-related obsessive-compulsive disorder: results from a large multicenter study
de Alvarenga P, de Mathis M, Alves A, do Rosário M, Fossaluza V, Hounie A, Miguel E, Torres A. Clinical features of tic-related obsessive-compulsive disorder: results from a large multicenter study. CNS Spectrums 2012, 17: 87-93. PMID: 22789066, DOI: 10.1017/s1092852912000491.Peer-Reviewed Original ResearchConceptsYale Global Tic Severity ScaleTic disordersComorbid tic disordersYale-Brown ObsessiveClinical featuresAnxiety disordersChronic vocal tic disorderDSM-IV Axis I DisordersTic-related obsessive-compulsive disorderChronic motor tic disorderCompulsive ScaleVocal tic disorderMotor tic disorderLarge multicenter studyCross-sectional studyStructured Clinical InterviewAxis I DisordersTic Severity ScaleObsessive-compulsive disorder patientsPost-traumatic stress disorderAttention deficit hyperactivity disorderSensory phenomenaSymptom onsetMulticenter studyMean ageClinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study
Torres A, Fontenelle L, Ferrão Y, do Rosário M, Torresan R, Miguel E, Shavitt R. Clinical features of obsessive-compulsive disorder with hoarding symptoms: A multicenter study. Journal Of Psychiatric Research 2012, 46: 724-732. PMID: 22464941, DOI: 10.1016/j.jpsychires.2012.03.005.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical featuresOCD patientsLogistic regressionDSM-IV OCD patientsCertain clinical featuresCross-sectional studyAttention-deficit/hyperactivity disorderStatistical univariate analysisBrazilian Research ConsortiumDeficit/hyperactivity disorderHigher anxiety scoresYale-Brown ObsessiveSymptom onsetInsidious onsetMulticenter studyObsessive-compulsive spectrum disordersSectional studyPossible confoundersUnivariate analysisTic disordersHoarding dimensionPatientsSymptomsPoor insight
2011
Towards a post-traumatic subtype of obsessive–compulsive disorder
Fontenelle L, Cocchi L, Harrison B, Shavitt R, do Rosário M, Ferrão Y, de Mathis M, Cordioli A, Yücel M, Pantelis C, de Jesus Mari J, Miguel E, Torres A. Towards a post-traumatic subtype of obsessive–compulsive disorder. Journal Of Anxiety Disorders 2011, 26: 377-383. PMID: 22230220, DOI: 10.1016/j.janxdis.2011.12.001.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderObsessive-compulsive symptomsOCD patientsPost-traumatic stress disorderOnset of OCDCompulsive buying disorderHistory of PTSDTraumatic eventsStress disorderBuying disorderOCD onsetPanic disorderPTSDAlcohol-related disordersClinical featuresDisordersEducational levelMultinomial logistic regression analysisLogistic regression analysisSuicide planEarly ageLow educational levelMiscellaneous symptomsLater ageRegression analysis
2010
Body dysmorphic disorder among dermatologic patients: Prevalence and clinical features
Conrado L, Hounie A, Diniz J, Fossaluza V, Torres A, Miguel E, Rivitti E. Body dysmorphic disorder among dermatologic patients: Prevalence and clinical features. Journal Of The American Academy Of Dermatology 2010, 63: 235-243. PMID: 20561712, DOI: 10.1016/j.jaad.2009.09.017.Peer-Reviewed Original ResearchConceptsBody dysmorphic disorderCosmetic groupClinical characteristicsDermatologic patientsDermatologic treatmentPrevalence of BDDDysmorphic disorderGeneral dermatology patientsCross-sectional studyMental health professionalsCosmetic settingsDermatology settingsClinical featuresPrevious diagnosisDermatology patientsControl subjectsUniversity HospitalDermatologic settingDermatology groupCurrent prevalencePatientsControl groupHealth professionalsPsychiatric conditionsRetrospective data
2008
Alcohol use disorders in patients with obsessive–compulsive disorder: The importance of appropriate dual-diagnosis
Gentil A, de Mathis M, Torresan R, Diniz J, Alvarenga P, do Rosário M, Cordioli A, Torres A, Miguel E. Alcohol use disorders in patients with obsessive–compulsive disorder: The importance of appropriate dual-diagnosis. Drug And Alcohol Dependence 2008, 100: 173-177. PMID: 19004577, DOI: 10.1016/j.drugalcdep.2008.09.010.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderYale-Brown ObsessiveAUD comorbidityPsychiatric treatmentSuicidal thoughtsClinical Global Impression ScaleCompulsive ScaleOCD patientsDSM-IV Axis IDSM-IV OCD patientsSpecific clinical featuresGlobal Impression ScaleAlcohol use disorder comorbidityCross-sectional studyStructured Clinical InterviewPrevious psychiatric treatmentAlcohol use disorderLifetime suicidal thoughtsLarge clinical sampleMental health professionalsClinical featuresImpression ScalePast alcoholClinical questionnaireSomatization disorderSex differences in the phenotypic expression of obsessive-compulsive disorder: an exploratory study from Brazil
Torresan R, de Abreu Ramos-Cerqueira A, de Mathis M, Diniz J, Ferrão Y, Miguel E, Torres A. Sex differences in the phenotypic expression of obsessive-compulsive disorder: an exploratory study from Brazil. Comprehensive Psychiatry 2008, 50: 63-69. PMID: 19059516, DOI: 10.1016/j.comppsych.2008.05.005.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderObsessive-compulsive symptomsBeck DepressionYale Global Tic Severity ScaleComorbid simple phobiasFemale Brazilian patientsStructured Clinical InterviewPrivate practice clinicTic Severity ScaleAnxiety InventoryComorbid tic disordersEfficacious treatment approachGlobal symptom severityPosttraumatic stress disorderSex-related differencesYale-Brown ObsessiveClinical characteristicsClinical featuresMean agePsychiatric comorbiditySymptom interferencePractice clinicsTic disordersBrazilian patientsFamily history
2007
Level of Insight and Clinical Features of Obsessive-Compulsive Disorder with and Without Body Dysmorphic Disorder
Nakata A, Diniz J, Torres A, de Mathis M, Fossaluza V, Bragancas C, Ferrão Y, Miguel E. Level of Insight and Clinical Features of Obsessive-Compulsive Disorder with and Without Body Dysmorphic Disorder. CNS Spectrums 2007, 12: 295-303. PMID: 17426667, DOI: 10.1017/s1092852900021052.Peer-Reviewed Original ResearchConceptsBody dysmorphic disorderClinical featuresObsessive-compulsive symptomsOCD patientsObsessive-compulsive disorderLevel of insightDysmorphic disorderPsychiatric comorbid disordersFourth Edition criteriaStructured Clinical InterviewComorbid body dysmorphic disorderLow educational levelEducational levelYale-Brown ObsessiveHigh morbidityPsychiatric comorbidityPossible confoundersEdition criteriaStudy groupComorbid disordersBrown AssessmentClinical InterviewPatientsBeck DepressionMental disorders
2006
Clinical features associated with treatment response in obsessive-compulsive disorder
Shavitt R, Belotto C, Curi M, Hounie A, Rosário-Campos M, Diniz J, Ferrão Y, Pato M, Miguel E. Clinical features associated with treatment response in obsessive-compulsive disorder. Comprehensive Psychiatry 2006, 47: 276-281. PMID: 16769302, DOI: 10.1016/j.comppsych.2005.09.001.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderClinical featuresPharmacological treatmentTreatment responseEarly onsetConsecutive adult patientsFourth Edition criteriaSensory phenomenaEarly-onset obsessive-compulsive disorderYale-Brown ObsessiveOral clomipramineClomipramine treatmentAdult patientsPoor prognosisPoor responseSao Paulo SchoolDisorders ClinicTic disordersEdition criteriaScore decreaseFavorable responseLinear regression analysisMental disordersStatistical ManualDisorders
2001
Transtorno obsessivo-compulsivo: possíveis subtipos
Hounie A, de A Brotto S, Diniz J, Chacon P, Miguel E. Transtorno obsessivo-compulsivo: possíveis subtipos. Brazilian Journal Of Psychiatry 2001, 23: 13-16. DOI: 10.1590/s1516-44462001000600005.Peer-Reviewed Original ResearchPutative subtypesUnderlying pathophysiological substrateEarly age onsetMore specific treatmentsGenetic family studiesExistence of subtypesRheumatic feverDisease coursePathophysiological substrateClinical featuresTreatment responseSpecific treatmentAge onsetPoor insightHeterogeneous disorderSubtypesPossible subgroupsFamily studiesSubgroupsOCDPhenotypic characterizationFeverGroupOCD and transvestism:is there a relationship?
Abdo C, Hounie A, De Tubino Scanavino M, Miguel E. OCD and transvestism:is there a relationship? Acta Psychiatrica Scandinavica 2001, 103: 471-473. PMID: 11401663, DOI: 10.1034/j.1600-0447.2001.00294.x.Peer-Reviewed Original Research
1994
Psychiatric Manifestations of Systemic Lupus Erythematosus: Clinical Features, Symptoms, and Signs of Central Nervous System Activity in 43 Patients
Miguel E, Pereira R, de Bragança Pereira C, Baer L, Gomes R, de Sá L, Hirsch R, de Barros N, de Navarro J, Gentil V. Psychiatric Manifestations of Systemic Lupus Erythematosus: Clinical Features, Symptoms, and Signs of Central Nervous System Activity in 43 Patients. Medicine 1994, 73: 224-232. PMID: 8041245, DOI: 10.1097/00005792-199407000-00005.Peer-Reviewed Original ResearchConceptsActive systemic lupus erythematosusSystemic lupus erythematosusCentral nervous system activityPsychiatric manifestationsNervous system activityPsychiatric symptomsLupus erythematosusDepressive syndromeActivity of SLEComputerized tomographyCerebral spinal fluid analysisCNS activityMild depressive syndromesSpinal fluid analysisBrain computerized tomographySystem activityGeneral clinical evaluationCurrent psychiatric diagnosisStandardized psychiatric instrumentsSubjective cognitive impairmentCSF examOphthalmologic evaluationClinical featuresFrequent diagnosisCT alterations
1990
Neuropsychiatric disorders in systemic lupus erythematosus: a multidisciplinary review.
Miguel Filho E, Pereira R, de Almeida O, Hirsch R, Lafer B, Fang T, Busatto Filho G, de Arruda P. Neuropsychiatric disorders in systemic lupus erythematosus: a multidisciplinary review. Sao Paulo Medical Journal 1990, 108: 174-82. PMID: 2095621.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusLupus erythematosusClinical featuresNeuropsychiatric alterationsPsychiatric changesChronic diseasesDifferential diagnosisPsychic symptomsNeuropsychiatric disordersPatientsDiseaseDiagnosisMultidisciplinary reviewCorticosteroidsErythematosusHypertensionUremiaPathogenesisSymptomsInfection