2014
Searching for the Immune Basis of Obsessive-Compulsive Disorder
Teixeira AL, Rodrigues DH, Marques AH, Miguel EC, Fontenelle LF. Searching for the Immune Basis of Obsessive-Compulsive Disorder. NeuroImmunoModulation 2014, 21: 152-158. PMID: 24557049, DOI: 10.1159/000356554.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderImmune parametersAnti-basal ganglia antibodiesParticular immune profileRheumatic feverImmune profileComorbid conditionsImmune basisAutoimmune diseasesImmune cellsPsychotropic drugsClinical observationsObsessive-compulsive symptomsPatientsUnequivocal changesOCD patientsElevated frequencyDisordersFeverEtiopathogenesisCytokinesSymptomsDiseaseAntibodies
2006
Association of polymorphisms within the promoter region of the tumor necrosis factor-α with clinical outcomes of rheumatic fever
Ramasawmy R, Faé K, Spina G, Victora G, Tanaka A, Palácios S, Hounie A, Miguel E, Oshiro S, Goldberg A, Kalil J, Guilherme L. Association of polymorphisms within the promoter region of the tumor necrosis factor-α with clinical outcomes of rheumatic fever. Molecular Immunology 2006, 44: 1873-1878. PMID: 17079017, DOI: 10.1016/j.molimm.2006.10.001.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAortic DiseasesAutoimmune DiseasesChildChoreaCohort StudiesFemaleGenetic Predisposition to DiseaseHumansMaleMyocarditisPolymorphism, Single NucleotidePredictive Value of TestsQuantitative Trait LociRheumatic Heart DiseaseStreptococcal InfectionsStreptococcus pyogenesTumor Necrosis Factor-alphaConceptsRheumatic feverRF patientsClinical outcomesHealthy controlsTNFA geneMinor alleleRF/RHDAortic valve lesionsRecognition of autoantigensStratification of patientsTumor necrosis factorAssociation of polymorphismsMild carditisValve lesionsAdaptive armsSydenham's choreaAutoimmune diseasesHeart diseaseInflammatory diseasesNecrosis factorBorderline associationG-308APatientsImmune systemClinical phenotype
1989
Catatonic syndrome caused by autoimmune disease: spontaneous remission.
Lichtenstein A, Calish I, Oliveira R, Miguel Filho E, Rocha A. Catatonic syndrome caused by autoimmune disease: spontaneous remission. Clinics 1989, 44: 312-5. PMID: 2486424.Peer-Reviewed Original ResearchConceptsCSF immune complexesAutoimmune diseasesImmune complexesCatatonic syndromeCerebrospinal fluidPositive antinuclear factorSystemic lupus erythematosusAntinuclear factorLupus erythematosusRare manifestationSystemic involvementSystemic manifestationsSpontaneous remissionImmunosuppressive drugsPsychiatric manifestationsCatatonic patientsImmunologic testsCase reportMetabolic disturbancesPsychiatric effectsNucleolar patternSchizophrenic disordersValuable markerDiseasePsychiatric picture