2020
Risk factors for obsessive–compulsive symptoms. Follow-up of a community-based youth cohort
Macul Ferreira de Barros P, do Rosário MC, Szejko N, Polga N, Requena GL, Ravagnani B, Fatori D, Batistuzzo MC, Hoexter MQ, Rohde LA, Polanczyk GV, Leckman JF, Miguel EC, de Alvarenga PG. Risk factors for obsessive–compulsive symptoms. Follow-up of a community-based youth cohort. European Child & Adolescent Psychiatry 2020, 30: 89-104. PMID: 32076869, DOI: 10.1007/s00787-020-01495-7.Peer-Reviewed Original ResearchConceptsObsessive-compulsive symptomsRisk factorsAbsence of breastfeedingOCS scoresBaseline anxiety disordersPotential risk factorsLarge community cohortLow socioeconomic statusRegression analysisMental health assessmentMaternal stress levelsLower intelligence quotientCommunity cohortChildhood adversityLower ageHigher OCS scoresAnxiety disordersPsychopathological factorsSocioeconomic statusGenetic factorsSignificant predictorsBaselineHealth assessmentScoresAge
2013
Symptom dimensions are associated with age of onset and clinical course of obsessive–compulsive disorder
Kichuk SA, Torres AR, Fontenelle LF, Rosário MC, Shavitt RG, Miguel EC, Pittenger C, Bloch MH. Symptom dimensions are associated with age of onset and clinical course of obsessive–compulsive disorder. Progress In Neuro-Psychopharmacology And Biological Psychiatry 2013, 44: 233-239. PMID: 23410525, PMCID: PMC3654083, DOI: 10.1016/j.pnpbp.2013.02.003.Peer-Reviewed Original ResearchConceptsAge of onsetClinical courseObsessive-compulsive disorderPrimary symptom dimensionsSymptom dimensionsPrimary OCD symptomsChi-square testEarly ageOCD symptom dimensionsYale-Brown ObsessiveAdult patientsComorbid ticsSignificant symptomsLarge cohortDifferent OCD symptom dimensionsHeterogeneous symptomsSymptomsCompulsive ScaleDimensional Yale-Brown ObsessiveAgeSignificant differencesOCD symptomsOnsetInconsistent results
2008
Obsessive–compulsive disorder: Influence of age at onset on comorbidity patterns
de Mathis M, do Rosario M, Diniz J, Torres A, Shavitt R, Ferrão Y, Fossaluza V, de Bragança Pereira C, Miguel E. Obsessive–compulsive disorder: Influence of age at onset on comorbidity patterns. European Psychiatry 2008, 23: 187-194. PMID: 18329252, DOI: 10.1016/j.eurpsy.2008.01.002.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge of OnsetAnxiety DisordersAttention Deficit Disorder with HyperactivityBrazilComorbidityCross-Sectional StudiesDisruptive, Impulse Control, and Conduct DisordersFeeding and Eating DisordersFemaleHumansMaleMental DisordersMiddle AgedObsessive-Compulsive DisorderPersonality AssessmentSex FactorsSomatoform DisordersTic DisordersConceptsImpulse control disordersInfluence of ageComorbidity patternsYale Global Tic Severity ScaleOCD patientsStructured Clinical InterviewTic Severity ScaleYale-Brown Obsessive Compulsive ScaleAttention-deficit/hyperactivity disorderObsessive Compulsive ScalePsychiatric comorbidityIllness durationTic disordersFemale genderSeverity ScaleClinical InterviewDSM-IVLower ageAnxiety disordersCompulsive ScaleHyperactivity disorderDisordersLower chanceAgeComorbidities
2001
Adults With Early-Onset Obsessive-Compulsive Disorder
Rosario-Campos MC, Leckman JF, Mercadante MT, Shavitt RG, Prado HS, Sada P, Zamignani D, Miguel EC. Adults With Early-Onset Obsessive-Compulsive Disorder. American Journal Of Psychiatry 2001, 158: 1899-1903. PMID: 11691698, DOI: 10.1176/appi.ajp.158.11.1899.Peer-Reviewed Original ResearchConceptsSymptom onsetObsessive-compulsive disorderSelective serotonin reuptake inhibitorsOCD patientsSerotonin reuptake inhibitorsEarlier symptom onsetEarly-onset groupLater symptom onsetOnset obsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleComorbid tic disordersAdult OCD patientsObsessive Compulsive ScaleReuptake inhibitorsAdult outpatientsTic disordersTreatment outcomesOCD symptom onsetBimodal ageEarly onsetHeterogeneous disorderCompulsive ScaleDisordersAgePatients