1998
Lyme Arthritis in Children: Clinical Epidemiology and Long-term Outcomes
Gerber M, Zemel L, Shapiro E. Lyme Arthritis in Children: Clinical Epidemiology and Long-term Outcomes. Pediatrics 1998, 102: 905-908. PMID: 9755263, DOI: 10.1542/peds.102.4.905.Peer-Reviewed Original ResearchConceptsLong-term outcomesLyme arthritisAppropriate antimicrobial therapyAntimicrobial therapyClinical epidemiologyLyme diseaseMean white blood cell countWhite blood cell countNewington Children's HospitalCells/mm3Pediatric rheumatology clinicTime of diagnosisEarly Lyme diseaseErythrocyte sedimentation rateLong-term followOnset of symptomsBlood cell countStructured telephone interviewActive arthritisChronic arthritisRheumatology clinicArthroscopic synovectomyInitial diagnosisChildren's HospitalTelephone follow
1996
Lyme Disease in Children in Southeastern Connecticut
Gerber M, Shapiro E, Burke G, Parcells V, Bell G. Lyme Disease in Children in Southeastern Connecticut. New England Journal Of Medicine 1996, 335: 1270-1274. PMID: 8857006, DOI: 10.1056/nejm199610243351703.Peer-Reviewed Original ResearchConceptsErythema migrans lesionsSingle erythema migrans lesionLyme diseaseErythema migransClinical manifestationsMultiple erythema migrans lesionsCommunity-based cohort studyFacial nerve palsyInitial clinical manifestationPrompt clinical responseEarly Lyme diseasePercent of childrenConventional antimicrobial therapyMultiple erythemaClinical responseCohort studyAseptic meningitisConsecutive patientsMedian ageProspective dataAntimicrobial therapyAntibody testNew episodesPatientsLesions
1994
Lyme Disease
Baltimore R, Shapiro E. Lyme Disease. Pediatrics In Review 1994, 15: 167-173. PMID: 8036192, DOI: 10.1542/pir.15-5-167.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsLyme diseaseLyme borreliosisCommon vector-borne diseaseIxodes ticksNymphal Ixodes ticksUnexplained arthritisLyme arthritisClinical manifestationsBacterial etiologyClusters of childrenBorrelia burgdoferiMedical attentionSystemic infectionArthritisDistinct entityDiseaseBorrelia burgdorferiPencil pointVector-borne diseasesBorreliosisTicksWood tickPatientsEtiologyYears
1986
Clinical features as predictors of functional status in children with cystic fibrosis
Katz J, Horwitz R, Dolan T, Shapiro E. Clinical features as predictors of functional status in children with cystic fibrosis. The Journal Of Pediatrics 1986, 108: 352-358. PMID: 3950815, DOI: 10.1016/s0022-3476(86)80872-1.Peer-Reviewed Original ResearchConceptsCystic fibrosisClinical courseClinical featuresGood clinical courseValuable prognostic indicatorPrevious clinical studiesClinical deteriorationGastrointestinal symptomsPrognostic indicatorFunctional statusClinical studiesRespiratory diseaseSurvival rateFibrosisPatientsDiagnosisSubsequent outcomesSubsequent survival ratesChildrenSymptomsOutcomesSubstantial variabilityInitial levelMorbidityYears