2008
Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats
Detloff MR, Fisher LC, McGaughy V, Longbrake EE, Popovich PG, Basso DM. Remote activation of microglia and pro-inflammatory cytokines predict the onset and severity of below-level neuropathic pain after spinal cord injury in rats. Experimental Neurology 2008, 212: 337-347. PMID: 18511041, PMCID: PMC2600773, DOI: 10.1016/j.expneurol.2008.04.009.Peer-Reviewed Original ResearchConceptsPeripheral nerve injuryL5 dorsal hornRemote microglial activationLevel allodyniaPro-inflammatory cytokinesMicroglial activationNeuropathic painNerve injuryDorsal hornLevel painPro-inflammatory cytokine productionActivator of microgliaLevel neuropathic painRobust microglial activationChronic time pointsSpinal cord injuryLevel of injuryAllodynic ratsChronic allodyniaModerate SCISupraspinal centersCord injuryCytokine productionIL-6IL-1beta
2006
REMOTE MICROGLIAL ACTIVATION AND THE PRODUCTION OF PROINFLAMMATORY CYTOKINES PREDICTS THE DEVELOPMENT OF NEUROPATHIC PAIN AFTER SPINAL CORD INJURY
Detlof M, Fisher L, McGaughy V, Longbrake E, Popovich P, Basso D. REMOTE MICROGLIAL ACTIVATION AND THE PRODUCTION OF PROINFLAMMATORY CYTOKINES PREDICTS THE DEVELOPMENT OF NEUROPATHIC PAIN AFTER SPINAL CORD INJURY. Journal Of Neurologic Physical Therapy 2006, 30: 202. DOI: 10.1097/01.npt.0000281277.85517.ec.Peer-Reviewed Original Research