Featured Publications
Myelin Oligodendrocyte Glycoprotein–Associated Disorders
Longbrake E. Myelin Oligodendrocyte Glycoprotein–Associated Disorders. CONTINUUM Lifelong Learning In Neurology 2022, 28: 1171-1193. PMID: 35938661, PMCID: PMC9523511, DOI: 10.1212/con.0000000000001127.Peer-Reviewed Original ResearchConceptsAcute disseminated encephalomyelitisClinical spectrumCentral nervous system autoimmune diseaseNatural historyFuture therapeutic trialsLarge cohort studyRecent case reportsDistinct clinical phenotypesDisseminated encephalomyelitisGlycoprotein autoantibodiesOptic neuritisCohort studyMost patientsRelapse patternsNeuromyelitis opticaTherapeutic trialsMultiple sclerosisAutoimmune diseasesCNS diseaseCase reportCNS diseasesAccurate diagnosisClinical phenotypeDiseaseDisorders
2021
Neuroinflammation Associated With Tumor Necrosis Factor-α Inhibitor Exposure
Yu AW, Pecsok M, Longbrake EE, Wesley SF. Neuroinflammation Associated With Tumor Necrosis Factor-α Inhibitor Exposure. Neurology Clinical Practice 2021, 11: e488-e496. PMID: 34484946, PMCID: PMC8382406, DOI: 10.1212/cpj.0000000000001014.Peer-Reviewed Original ResearchMRI findingsBrain MRIYale New Haven Health SystemNonspecific MRI findingsRetrospective cohort studyCommon abnormal findingDetailed chart reviewRisk stratification parametersElectronic medical recordsAdditional immunotherapyNeuroinflammatory phenomenaTNFi discontinuationTNFi exposureChart reviewCohort studyAbnormal findingsPeriod prevalenceT2 hyperintensityAutoimmune diseasesClinical spectrumInhibitor exposureMedical recordsTumor necrosisTNFiNeuroinflammation