2017
CDK4/6 inhibition triggers anti-tumour immunity
Goel S, DeCristo MJ, Watt AC, BrinJones H, Sceneay J, Li BB, Khan N, Ubellacker JM, Xie S, Metzger-Filho O, Hoog J, Ellis MJ, Ma CX, Ramm S, Krop IE, Winer EP, Roberts TM, Kim HJ, McAllister SS, Zhao JJ. CDK4/6 inhibition triggers anti-tumour immunity. Nature 2017, 548: 471-475. PMID: 28813415, PMCID: PMC5570667, DOI: 10.1038/nature23465.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigen PresentationBiological MimicryBreast NeoplasmsCell Cycle CheckpointsCell Line, TumorCell ProliferationCyclin-Dependent Kinase 4Cyclin-Dependent Kinase 6Disease Models, AnimalFemaleHumansInterferonsMicePhosphorylationProtein Kinase InhibitorsRepressor ProteinsRNA, Double-StrandedSignal TransductionT-Lymphocytes, RegulatoryTranscriptomeViruses
2015
Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial
Metzger Filho O, Giobbie-Hurder A, Mallon E, Gusterson B, Viale G, Winer EP, Thürlimann B, Gelber RD, Colleoni M, Ejlertsen B, Debled M, Price KN, Regan MM, Coates AS, Goldhirsch A. Relative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 Trial. Journal Of Clinical Oncology 2015, 33: 2772-2779. PMID: 26215945, PMCID: PMC4550691, DOI: 10.1200/jco.2015.60.8133.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntineoplastic Agents, HormonalAntineoplastic Combined Chemotherapy ProtocolsAromatase InhibitorsBiomarkers, TumorBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, LobularChemotherapy, AdjuvantDisease-Free SurvivalFemaleHumansKi-67 AntigenLetrozoleMiddle AgedNitrilesReceptor, ErbB-2TamoxifenTreatment OutcomeTriazolesConceptsInvasive ductal carcinomaInvasive lobular carcinomaDisease-free survivalLobular carcinomaDFS eventsDuctal carcinomaLA subtypeBreast International Group (BIG) 1Early-stage invasive ductal carcinomaClassic invasive lobular carcinomaHER2-negative invasive ductal carcinomaKi-67 labeling indexLow proliferative activityMagnitude of benefitAdjuvant letrozoleMedian followBIG 1ILC subsetsMultivariable modelCox modelGroup 1LetrozoleCarcinomaLabeling indexPatientsAcute appendicitis secondary to metastatic carcinoma of the breast: Case report and review of the literature
Tahara R, Keraliya A, Ramaiya N, Ritterhouse L, Winer E, Tolaney S. Acute appendicitis secondary to metastatic carcinoma of the breast: Case report and review of the literature. Cancer Treatment And Research Communications 2015, 4: 41-45. DOI: 10.1016/j.ctrc.2015.04.001.Peer-Reviewed Original Research
2013
Long‐Term Risk Perceptions of Women With Ductal Carcinoma In Situ
Ruddy KJ, Meyer ME, Giobbie‐Hurder A, Emmons KM, Weeks JC, Winer EP, Partridge AH. Long‐Term Risk Perceptions of Women With Ductal Carcinoma In Situ. The Oncologist 2013, 18: 362-368. PMID: 23568001, PMCID: PMC3639521, DOI: 10.1634/theoncologist.2012-0376.Peer-Reviewed Original ResearchConceptsInvasive breast cancerBreast cancerDuctal carcinomaLifetime riskFuture breast cancer eventsHistory of DCISBreast cancer eventsTime of diagnosisLong-term followLongitudinal cohort studyFuture breast cancerWorse financial statusCohort studyMedian timeCancer eventsDCISOnly predictorModerate riskMultivariate modelCancerWomenDiagnosisRisk perceptionCarcinomaRecurrence
2010
The role of socioeconomic status in adjustment after ductal carcinoma in situ
de Moor JS, Partridge AH, Winer EP, Ligibel J, Emmons KM. The role of socioeconomic status in adjustment after ductal carcinoma in situ. Cancer 2010, 116: 1218-1225. PMID: 20143325, PMCID: PMC3072709, DOI: 10.1002/cncr.24832.Peer-Reviewed Original ResearchConceptsLow socioeconomic statusSocioeconomic statusDuctal carcinomaSocial supportTime of enrollmentImpact of SESDCIS diagnosisClinical characteristicsLow financial statusClinical depressionPhysical healthStudy periodFinancial statusWomenDepressionLow SESCarcinomaDistressAnxietyDiagnosisHigher financial statusStatusCurrent studyAssociation
2008
Perceptions and Management Approaches of Physicians Who Care for Women with Ductal Carcinoma In Situ
Partridge A, Winer JP, Golshan M, Bellon JR, Blood E, Dees EC, Sampson E, Emmons KM, Winer E. Perceptions and Management Approaches of Physicians Who Care for Women with Ductal Carcinoma In Situ. Clinical Breast Cancer 2008, 8: 275-280. PMID: 18650159, DOI: 10.3816/cbc.2008.n.032.Peer-Reviewed Original ResearchConceptsDuctal carcinomaBreast cancerOverall healthPatient's overall healthLongitudinal cohort studyCohort studyMedian ageMedical oncologistsEligible physiciansPatient outcomesMultivariable modelPhysicians' perceptionsDCISNew patientsPatientsResponse rateFurther evaluationTheoretical patientsPhysiciansWomenMore womenCarcinomaCancerRisky diseaseRisk
2007
Follow-up care of patients with breast cancer
Tolaney SM, Winer EP. Follow-up care of patients with breast cancer. The Breast 2007, 16: 45-50. PMID: 17697780, DOI: 10.1016/j.breast.2007.07.005.Peer-Reviewed Original ResearchConceptsBreast cancerEarly detectionNew primary cancerInvasive breast cancerBreast cancer survivorsLong-term complicationsRoutine imaging studiesCare of patientsLocoregional recurrenceDistant metastasisPrimary cancerCancer survivorsDuctal carcinomaNew casesSurveillance strategiesImaging studiesCancerFurther studiesRecurrenceCareWomenComplicationsPatientsCarcinomaMetastasis
2005
Offering participants results of a clinical trial: sharing results of a negative study
Partridge AH, Wong JS, Knudsen K, Gelman R, Sampson E, Gadd M, Bishop KL, Harris JR, Winer EP. Offering participants results of a clinical trial: sharing results of a negative study. The Lancet 2005, 365: 963-964. PMID: 15766998, DOI: 10.1016/s0140-6736(05)71085-0.Peer-Reviewed Original ResearchConceptsClinical trialsNegative studiesPhase II trialClinical trial resultsClinical trial participantsII trialLocal recurrenceDuctal carcinomaBreast excisionTrial participantsResults of trialsTrial resultsTrialsMost participantsHigh ratePreliminary findingsWomenParticipantsPatientsCarcinomaRecurrenceExcisionEarly high rate
2001
Knowledge, Satisfaction, and Perceived Cancer Risk among Women Diagnosed with Ductal Carcinoma In Situ
Bluman L, Borstelmann N, Rimer B, Iglehart J, Winer E. Knowledge, Satisfaction, and Perceived Cancer Risk among Women Diagnosed with Ductal Carcinoma In Situ. Journal Of Women's Health 2001, 10: 589-598. PMID: 11559456, DOI: 10.1089/15246090152543175.Peer-Reviewed Original ResearchConceptsDuctal carcinomaBreast cancerInvasive breast cancerSelf-administered questionnaireDCIS diagnosisTumor RegistryDCISCancer riskFuture healthKnowledge deficitsPsychological distressWomenCarcinomaCancerRisk perceptionCareFuture studiesFuture investigationsAreas of concernPrognosisRecurrenceWidespread useMetastasisRegistryPrevalence
1998
Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk.
Frank TS, Manley SA, Olopade OI, Cummings S, Garber JE, Bernhardt B, Antman K, Russo D, Wood ME, Mullineau L, Isaacs C, Peshkin B, Buys S, Venne V, Rowley PT, Loader S, Offit K, Robson M, Hampel H, Brener D, Winer EP, Clark S, Weber B, Strong LC, Thomas A. Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk. Journal Of Clinical Oncology 1998, 16: 2417-25. PMID: 9667259, DOI: 10.1200/jco.1998.16.7.2417.Peer-Reviewed Original Research