2016
Impact of neoadjuvant therapy on eligibility for and frequency of breast conservation in stage II–III HER2-positive breast cancer: surgical results of CALGB 40601 (Alliance)
Golshan M, Cirrincione CT, Sikov WM, Carey LA, Berry DA, Overmoyer B, Henry NL, Somlo G, Port E, Burstein HJ, Hudis C, Winer E, Ollila DW, for the Alliance for Clinical Trials in Oncology. Impact of neoadjuvant therapy on eligibility for and frequency of breast conservation in stage II–III HER2-positive breast cancer: surgical results of CALGB 40601 (Alliance). Breast Cancer Research And Treatment 2016, 160: 297-304. PMID: 27704226, PMCID: PMC5189982, DOI: 10.1007/s10549-016-4006-6.Peer-Reviewed Original ResearchConceptsNeoadjuvant systemic therapyBreast-conserving therapyBCT-eligible patientsPathologic complete responseSuccessful breast-conserving therapyHER2-positive breast cancerBCT eligibilityPCR rateBreast conservationSurgical assessmentBreast cancerStage IIHigh clinical response rateFinal surgical procedureClinical response rateSubset of patientsManagement of patientsPoor cosmetic outcomeSuccess rateCALGB 40601Converted patientsNeoadjuvant trialsNeoadjuvant therapyPrimary surgeryMulticentric disease
2008
Trends in Racial and Age Disparities in Definitive Local Therapy of Early-Stage Breast Cancer
Freedman RA, He Y, Winer EP, Keating NL. Trends in Racial and Age Disparities in Definitive Local Therapy of Early-Stage Breast Cancer. Journal Of Clinical Oncology 2008, 27: 713-719. PMID: 19103731, DOI: 10.1200/jco.2008.17.9234.Peer-Reviewed Original ResearchConceptsDefinitive local therapyBreast-conserving surgeryEarly-stage breast cancerLocal therapyBreast cancerHispanic womenStage I/II breast cancerEnd Results registry dataAsian womenReceipt of radiationMultivariate logistic regressionBreast cancer therapyRace/ethnicityMastectomy ratesTherapy ratesBreast conservationAdjusted analysisRegistry dataWomen 61Stage ITherapyAdult womenLogistic regressionCancerStudy period
2007
Does MRI predict pathologic tumor response in women with breast cancer undergoing preoperative chemotherapy?
Segara D, Krop IE, Garber JE, Winer E, Harris L, Bellon JR, Birdwell R, Lester S, Lipsitz S, Iglehart JD, Golshan M. Does MRI predict pathologic tumor response in women with breast cancer undergoing preoperative chemotherapy? Journal Of Surgical Oncology 2007, 96: 474-480. PMID: 17640031, DOI: 10.1002/jso.20856.Peer-Reviewed Original ResearchConceptsNeoadjuvant therapyNeoadjuvant chemotherapyPreoperative chemotherapyTumor sizePhysical examBreast cancerFinal pathologic tumor sizePathologic tumor sizeStart of therapyInvasive breast cancerBreast cancer patientsPathologic tumor responseCorrelation of ultrasoundUse of MRIPhysical exam dataComplete respondersBreast conservationPathologic sizeCancer patientsPathology sizeTumor responseUS assessmentPathologic measurementsPathology responsePatients