2008
Evaluation of mechanical dyssynchrony and myocardial perfusion using phase analysis of gated SPECT imaging in patients with left ventricular dysfunction
Trimble MA, Borges-Neto S, Honeycutt EF, Shaw LK, Pagnanelli R, Chen J, Iskandrian AE, Garcia EV, Velazquez EJ. Evaluation of mechanical dyssynchrony and myocardial perfusion using phase analysis of gated SPECT imaging in patients with left ventricular dysfunction. Journal Of Nuclear Cardiology 2008, 15: 663-670. PMID: 18761269, PMCID: PMC3048059, DOI: 10.1016/j.nuclcard.2008.06.007.Peer-Reviewed Original ResearchConceptsLeft ventricular dysfunctionMechanical dyssynchronyQRS durationPhase SDHF patientsVentricular dysfunctionPerfusion abnormalitiesMyocardial perfusionGated SPECT myocardial perfusion imagingLV phase distributionPhase analysis indicesSPECT myocardial perfusion imagingHeart failure patientsCardiac resynchronization therapyMeasures of dyssynchronyMyocardial perfusion imagingSingle photon emissionLV dysfunctionFailure patientsResynchronization therapyEjection fractionElectrical dyssynchronyMyocardial functionDyssynchronyMyocardial thickeningRepeatability and reproducibility of phase analysis of gated single-photon emission computed tomography myocardial perfusion imaging used to quantify cardiac dyssynchrony
Trimble MA, Velazquez EJ, Adams GL, Honeycutt EF, Pagnanelli RA, Barnhart HX, Chen J, Iskandrian AE, Garcia EV, Borges-Neto S. Repeatability and reproducibility of phase analysis of gated single-photon emission computed tomography myocardial perfusion imaging used to quantify cardiac dyssynchrony. Nuclear Medicine Communications 2008, 29: 374-381. PMID: 18317303, PMCID: PMC3048057, DOI: 10.1097/mnm.0b013e3282f81380.Peer-Reviewed Original ResearchConceptsSingle photon emissionLeft ventricular dysfunctionTomography perfusion imagingPhase standard deviationNormal controlsPerfusion imagingVentricular dysfunctionTomography myocardial perfusion imagingMyocardial perfusion imagingIntraclass correlation coefficientCardiac dyssynchronyDyssynchronyPatientsInterobserver comparisonsIntraobserver comparisonsDysfunctionPhase indexMean absolute differenceImaging
2007
Mortality risk associated with ejection fraction differs across resting nuclear perfusion findings
Bourque JM, Velazquez EJ, Tuttle RH, Shaw LK, O’Connor C, Borges-Neto S. Mortality risk associated with ejection fraction differs across resting nuclear perfusion findings. Journal Of Nuclear Cardiology 2007, 14: 165-173. PMID: 17386378, DOI: 10.1016/j.nuclcard.2006.11.011.Peer-Reviewed Original ResearchConceptsMortality riskEjection fractionPrognostic informationHigher long-term mortality ratesLong-term mortality ratesPerfusion single-photon emissionVentricular ejection fractionIschemic heart diseaseLong-term outcomesProportional hazard modelingLong-term survivalSingle photon emissionCardiac catheterizationNormal LVEFRisk stratificationPerfusion findingsPatient prognosticationHeart diseaseRest scoreLVEFMyocardial perfusionMortality ratePerfusion studiesHazard modelingSignificant predictors