Impact of early surgery on survival of patients with severe mitral regurgitation
Samad Z, Kaul P, Shaw LK, Glower DD, Velazquez EJ, Douglas PS, Jollis JG. Impact of early surgery on survival of patients with severe mitral regurgitation. Heart 2010, 97: 221. PMID: 21071750, DOI: 10.1136/hrt.2010.202432.Peer-Reviewed Original ResearchConceptsSevere mitral regurgitationDegenerative mitral regurgitationEarly surgery groupLate surgery groupEarly surgeryMitral regurgitationSurgery groupLate surgeryGuideline indicationsOptimal timingValve diseaseMV repairAdjusted Cox regression modelCongenital mitral valve diseaseValve repair/replacementSevere degenerative mitral regurgitationACC/AHA guideline recommendationsSevere valve diseaseSurvival of patientsTiming of surgeryMitral valve diseaseCox regression modelLong-term survivalEarly referralCoronary disease