2011
Circumstances and Outcomes of Sudden Unexpected Death in Patients With High-Risk Myocardial Infarction
Ye S, Grunnert M, Thune JJ, Stephenson KM, Uno H, Finn PV, McMurray JJ, Velazquez EJ, Califf R, Pfeffer MA, Solomon SD. Circumstances and Outcomes of Sudden Unexpected Death in Patients With High-Risk Myocardial Infarction. Circulation 2011, 123: 2674-2680. PMID: 21606398, DOI: 10.1161/circulationaha.110.990655.Peer-Reviewed Original ResearchConceptsHigh-risk myocardial infarctionSudden deathMyocardial infarctionHospital eventsVentricular tachycardia/ventricular fibrillationPrevention of SDSD eventsLong-term mortalityMajority of patientsSudden unexpected deathInitial ECG rhythmCatastrophic complicationUnwitnessed arrestsUnexpected deathVentricular fibrillationTrial trialsPatientsInfarctionECG rhythmDeathPreventionHigher proportionHome eventsArrestSource documentationResponse to Letter Regarding Article, “Pathogenesis of Sudden Unexpected Death in a Clinical Trial of Patients With Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both”
Pouleur A, Barkoudah E, Uno H, Skali H, Finn P, Zelenkofske S, Belenkov Y, Mareev V, Velazquez E, Rouleau J, Maggioni A, Køber L, Califf R, McMurray J, Pfeffer M, Solomon S. Response to Letter Regarding Article, “Pathogenesis of Sudden Unexpected Death in a Clinical Trial of Patients With Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both”. Circulation 2011, 123: e586-e587. DOI: 10.1161/circulationaha.111.021600.Commentaries, Editorials and Letters
2010
Pathogenesis of Sudden Unexpected Death in a Clinical Trial of Patients With Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both
Pouleur AC, Barkoudah E, Uno H, Skali H, Finn PV, Zelenkofske SL, Belenkov YN, Mareev V, Velazquez EJ, Rouleau JL, Maggioni AP, Køber L, Califf RM, McMurray JJ, Pfeffer MA, Solomon SD. Pathogenesis of Sudden Unexpected Death in a Clinical Trial of Patients With Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both. Circulation 2010, 122: 597-602. PMID: 20660803, DOI: 10.1161/circulationaha.110.940619.Peer-Reviewed Original ResearchConceptsSudden unexpected deathRecurrent MISudden deathArrhythmic deathAutopsy recordsUnexpected deathAcute Myocardial Infarction trialImplantable cardioverter-defibrillator therapyEarly post-myocardial infarction periodPost-myocardial infarction periodMyocardial Infarction trialCardioverter-defibrillator therapySudden death eventsIndex MILack of benefitSeries of casesCardiovascular causesNoncardiovascular causesVentricular dysfunctionAcute MICardiac ruptureHeart failureAutopsy evidenceClinical groundsAutopsy findings
2005
Sudden Death in Patients with Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both
Solomon SD, Zelenkofske S, McMurray JJ, Finn PV, Velazquez E, Ertl G, Harsanyi A, Rouleau JL, Maggioni A, Kober L, White H, Van de Werf F, Pieper K, Califf RM, Pfeffer MA. Sudden Death in Patients with Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both. New England Journal Of Medicine 2005, 352: 2581-2588. PMID: 15972864, DOI: 10.1056/nejmoa043938.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionVentricular ejection fractionLeft ventricular dysfunctionMyocardial infarctionCardiac arrestSudden deathVentricular dysfunctionEjection fractionHeart failureLeft ventricular systolic functionHigh-risk patientsVentricular systolic functionSudden unexpected deathAcute myocardial infarctionCardiac causesHospital dischargeSystolic functionPercent confidence intervalsUnexpected deathHigh riskInfarctionPatientsResuscitationDysfunctionDeath