Mitral regurgitation in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: prognostic significance and relation to ventricular size and function
Amigoni M, Meris A, Thune JJ, Mangalat D, Skali H, Bourgoun M, Warnica JW, Barvik S, Arnold JM, Velazquez EJ, Van de Werf F, Ghali J, McMurray JJ, Køber L, Pfeffer MA, Solomon SD. Mitral regurgitation in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: prognostic significance and relation to ventricular size and function. European Heart Journal 2007, 28: 326-333. PMID: 17251259, DOI: 10.1093/eurheartj/ehl464.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiac VolumeDisease ProgressionEchocardiography, Doppler, ColorElectrocardiographyFemaleHeart FailureHumansMaleMiddle AgedMitral Valve InsufficiencyMyocardial InfarctionObserver VariationPrognosisProspective StudiesRandomized Controlled Trials as TopicRisk FactorsVentricular Dysfunction, LeftVentricular RemodelingConceptsProgression of MRBaseline mitral regurgitationHeart failureMitral regurgitationAcute myocardial infarctionMyocardial infarctionVentricular sizeMR severityHigh-risk myocardial infarctionModerate-severe mitral regurgitationBaseline MR severityWorse LV functionEnd-systolic volumeLarger LV volumesRegurgitant jet areaAtrial area ratioCV mortalityHF hospitalizationCardiovascular outcomesSystolic dysfunctionVentricular dysfunctionEjection fractionIndependent predictorsClinical outcomesLV function