Sex Differences in Platelet Reactivity and Cardiovascular and Psychological Response to Mental Stress in Patients With Stable Ischemic Heart Disease Insights From the REMIT Study
Samad Z, Boyle S, Ersboll M, Vora AN, Zhang Y, Becker RC, Williams R, Kuhn C, Ortel TL, Rogers JG, O’Connor C, Velazquez EJ, Jiang W, Investigators R. Sex Differences in Platelet Reactivity and Cardiovascular and Psychological Response to Mental Stress in Patients With Stable Ischemic Heart Disease Insights From the REMIT Study. Journal Of The American College Of Cardiology 2014, 64: 1669-1678. PMID: 25323254, PMCID: PMC4752118, DOI: 10.1016/j.jacc.2014.04.087.Peer-Reviewed Original ResearchConceptsMental stress-induced myocardial ischemiaIschemic heart diseaseStable ischemic heart diseaseLeft ventricular ejection fractionPlatelet aggregation responseMental stress taskMental stressTransthoracic echocardiographyPlatelet reactivityStress-induced myocardial ischemiaIschemic ST-segment changesRegional wall motion abnormalitiesAggregation responseStress taskMost baseline characteristicsVentricular ejection fractionHigher baseline depressionLong-term outcomesST-segment changesWall motion abnormalitiesPlatelet aggregation studiesSex differencesBaseline characteristicsBlood pressureEjection fraction