2016
Aortic valve surgery and survival in patients with moderate or severe aortic stenosis and left ventricular dysfunction
Samad Z, Vora AN, Dunning A, Schulte PJ, Shaw LK, Al-Enezi F, Ersboll M, McGarrah RW, Vavalle JP, Shah SH, Kisslo J, Glower D, Harrison JK, Velazquez EJ. Aortic valve surgery and survival in patients with moderate or severe aortic stenosis and left ventricular dysfunction. European Heart Journal 2016, 37: 2276-2286. PMID: 26787441, PMCID: PMC5841220, DOI: 10.1093/eurheartj/ehv701.Peer-Reviewed Original ResearchConceptsAortic valve surgerySevere aortic stenosisModerate aortic stenosisAortic stenosisValve surgeryMean gradientMultivariable Cox modelVentricular systolic dysfunctionCoronary artery bypassHigh-risk cohortCurrent practice patternsArtery bypassCause mortalityEchocardiographic databaseSystolic dysfunctionVentricular dysfunctionMultivariable adjustmentTranscatheter approachMedical therapyPractice patternsBetter survivalCABGCox modelPatientsLower mortality
2014
Surgical Revascularization Is Associated With Maximal Survival in Patients With Ischemic Mitral Regurgitation
Castleberry AW, Williams JB, Daneshmand MA, Honeycutt E, Shaw LK, Samad Z, Lopes RD, Alexander JH, Mathew JP, Velazquez EJ, Milano CA, Smith PK. Surgical Revascularization Is Associated With Maximal Survival in Patients With Ischemic Mitral Regurgitation. Circulation 2014, 129: 2547-2556. PMID: 24744275, PMCID: PMC4142433, DOI: 10.1161/circulationaha.113.005223.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery BypassDatabases, BibliographicFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHumansKaplan-Meier EstimateMaleMiddle AgedMitral ValveMitral Valve InsufficiencyMyocardial IschemiaMyocardial RevascularizationPercutaneous Coronary InterventionProportional Hazards ModelsRetrospective StudiesRisk FactorsSeverity of Illness IndexStentsConceptsIschemic mitral regurgitationPercutaneous coronary interventionMitral valve repairSignificant coronary artery diseaseSevere ischemic mitral regurgitationCoronary artery diseaseMitral regurgitationCoronary interventionValve repairMedical treatmentArtery diseaseTreatment strategiesLower mortalityMultivariable Cox proportional hazards analysisCox proportional hazards analysisCoronary artery bypassMitral valve surgeryKaplan-Meier methodProportional hazards analysisMitral regurgitation severitySurgical revascularizationArtery bypassValve surgeryOptimal treatmentCABG
2005
Left Ventricular Assessment in Myocardial Infarction: The VALIANT Registry
Hernandez AF, Velazquez EJ, Solomon SD, Kilaru R, Diaz R, O’Connor C, Ertl G, Maggioni AP, Rouleau JL, van Gilst W, Pfeffer MA, Califf RM. Left Ventricular Assessment in Myocardial Infarction: The VALIANT Registry. JAMA Internal Medicine 2005, 165: 2162-2169. PMID: 16217008, DOI: 10.1001/archinte.165.18.2162.Peer-Reviewed Original ResearchConceptsHeart failureMyocardial infarctionLV assessmentCardiac catheterizationVentricular assessmentAcute Myocardial Infarction RegistryAngiotensin-converting enzyme inhibitorClinical heart failureMyocardial Infarction RegistryLeft ventricular functionAcute myocardial infarctionQuality of careHospital mortalityHospital outcomesHospital stayBaseline characteristicsDischarge medicationsVentricular functionMultivariable modelPatientsPropensity analysisEnzyme inhibitorsLower mortalityCatheterizationEchocardiography