Rationale and design of the avoiding cardiovascular events through combination therapy in patients living with systolic hypertension (ACCOMPLISH) trialThe first randomized controlled trial to compare the clinical outcome effects of first-line combination therapies in hypertension
JAMERSON K, BAKRIS G, WUN C, DAHLOF B, LEFKOWITZ M, MANFREDA S, PITT B, VELAZQUEZ E, WEBER M. Rationale and design of the avoiding cardiovascular events through combination therapy in patients living with systolic hypertension (ACCOMPLISH) trialThe first randomized controlled trial to compare the clinical outcome effects of first-line combination therapies in hypertension. American Journal Of Hypertension 2004, 17: 793-801. DOI: 10.1016/s0895-7061(04)00840-4.Peer-Reviewed Original ResearchConceptsCombination therapyFirst-line combination therapyCardiovascular eventsTherapyOutcome effectsHypertensionPatientsTrials