2019
Plastic Deformation and Fragmentation of Strained Actin Filaments
Schramm AC, Hocky GM, Voth GA, Martiel JL, De La Cruz EM. Plastic Deformation and Fragmentation of Strained Actin Filaments. Biophysical Journal 2019, 117: 453-463. PMID: 31301801, PMCID: PMC6697348, DOI: 10.1016/j.bpj.2019.06.018.Peer-Reviewed Original Research
2015
Mechanical Heterogeneity Favors Fragmentation of Strained Actin Filaments
De La Cruz EM, Martiel JL, Blanchoin L. Mechanical Heterogeneity Favors Fragmentation of Strained Actin Filaments. Biophysical Journal 2015, 108: 2270-2281. PMID: 25954884, PMCID: PMC4423049, DOI: 10.1016/j.bpj.2015.03.058.Peer-Reviewed Original ResearchConceptsMechanical propertiesFilament deformationEnergy densityElastic energyLocal shear forcesDeformation modesFilament strainFilament mechanical propertiesCompliant segmentsMechanical heterogeneityCompressive forceShear forceDeformationFree energy densityElastic free energy densityTwisting rigiditiesShape deformationLocal discontinuitiesSpatial confinementElasticitySevering efficiencyEnergyEnergy gradientConfinementForce