2020
Rural–Urban Disparities in Intracerebral Hemorrhage Mortality in the USA: Preliminary Findings from the National Inpatient Sample
Otite F, Akano E, Akintoye E, Khandelwal P, Malik A, Chaturvedi S, Rosand J. Rural–Urban Disparities in Intracerebral Hemorrhage Mortality in the USA: Preliminary Findings from the National Inpatient Sample. Neurocritical Care 2020, 32: 715-724. PMID: 32232726, PMCID: PMC7223184, DOI: 10.1007/s12028-020-00950-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAphasiaCerebral HemorrhageComorbidityCraniotomyDeglutition DisordersFemaleHealthcare DisparitiesHospital Bed CapacityHospital MortalityHospitals, RuralHospitals, UrbanHumansHydrocephalusMaleMiddle AgedRespiration, ArtificialRisk FactorsUnited StatesYoung AdultConceptsNational Inpatient SampleSex-adjusted mortalityUrban hospitalRural hospitalsICH patientsInpatient SampleJoinpoint regressionIntracerebral hemorrhage mortalityMultivariable-adjusted modelsOdds of mortalityIntracerebral hemorrhage patientsCases of ICHHospital deathHospital mortalityMultivariable adjustmentUrban patientsRural patientsStroke careHemorrhage patientsMedicare insuranceRural-urban disparitiesPatientsResultsFrom 2004HospitalMortality gap
2019
Palliative care referral in ST-segment elevation myocardial infarction complicated with cardiogenic shock in the United States
Ando T, Akintoye E, Uemura T, Adegbala O, Ashraf S, Pahuja M, Shokr M, Takagi H, Grines C, Afonso L, Briasoulis A. Palliative care referral in ST-segment elevation myocardial infarction complicated with cardiogenic shock in the United States. Heart & Lung 2019, 49: 25-29. PMID: 31703953, DOI: 10.1016/j.hrtlng.2019.10.005.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPalliative care referralElevation myocardial infarctionPC referralSTEMI-CSCardiogenic shockCare referralMyocardial infarctionMechanical circulatory support useCoronary artery bypass graftStudy periodPC referral rateArtery bypass graftExtended care facilitiesNationwide Inpatient SampleEdition Clinical ModificationTrends of utilizationLow-income statusPC encountersPC consultationBypass graftMultivariable analysisInpatient SampleReferral ratesHigh comorbidityTrends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014)
Inampudi C, Akintoye E, Bengaluru Jayanna M, Asleh R, Briasouli A, Alvarez P, Briasoulis A. Trends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014). Journal Of Cardiac Failure 2019, 25: 524-533. PMID: 30844441, DOI: 10.1016/j.cardfail.2019.02.020.Peer-Reviewed Original ResearchConceptsLength of stayEnd-stage renal disease patientsHF admissionsRenal disease patientsHospital mortalityNonroutine dischargeHeart failureESRD patientsDisease patientsStudy periodAnnual national ratesHF admission ratesPrevalence of comorbiditiesIn-Hospital MortalityNational Inpatient SampleCost of hospitalizationAnnual percentage changeYears of ageHF hospitalizationSecondary admissionsAdmission diagnosisComorbidity prevalencePeritoneal dialysisSubgroup analysisInpatient Sample
2018
Racial/ethnic differences in the prognostic utility of left ventricular mass index for incident cardiovascular disease
Akintoye E, Mahmoud K, Shokr M, Sandio A, Mallikethi‐Reddy S, Sheikh M, Adegbala O, Egbe A, Briasoulis A, Afonso L. Racial/ethnic differences in the prognostic utility of left ventricular mass index for incident cardiovascular disease. Clinical Cardiology 2018, 41: 502-509. PMID: 29663526, PMCID: PMC6490106, DOI: 10.1002/clc.22914.Peer-Reviewed Original ResearchMeSH KeywordsAgedAsianBlack or African AmericanCardiovascular DiseasesComorbidityDatabases, FactualDisease ProgressionFemaleHispanic or LatinoHumansHypertrophy, Left VentricularIncidenceMagnetic Resonance Imaging, CineMaleMiddle AgedPredictive Value of TestsPrognosisProportional Hazards ModelsRacial GroupsRisk FactorsTime FactorsUnited StatesVentricular Function, LeftVentricular RemodelingWhite PeopleConceptsLeft ventricular mass indexLeft ventricular hypertrophyNon-Hispanic whitesVentricular mass indexCVD eventsIncident CVDMass indexPrognostic utilityEthnic differencesFuture cardiovascular disease eventsOptimal cutpointCardiovascular disease eventsFuture CVD eventsIncident cardiovascular diseaseRisk stratification strategiesIncident cardiovascular outcomesMulti-Ethnic StudyRace/ethnicityCardiovascular outcomesLVMI valuesVentricular hypertrophyCardiovascular diseaseDisease eventsCox modelStratification strategiesFinancial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database)
Abubakar H, Yassin A, Akintoye E, Bakhit K, Pahuja M, Shokr M, Lieberman R, Afonso L. Financial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database). The American Journal Of Cardiology 2018, 121: 1587-1592. PMID: 29622287, DOI: 10.1016/j.amjcard.2018.02.052.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Valve StenosisArrhythmias, CardiacAtrial FibrillationCardiac Pacing, ArtificialCardiac TamponadeComorbidityDatabases, FactualFemaleHeart ArrestHeart FailureHospital CostsHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMyocardial InfarctionPacemaker, ArtificialPericardial EffusionPostoperative ComplicationsPostoperative HemorrhageStrokeTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationPre-existing atrial fibrillationLength of stayPeriprocedural cardiac complicationsAortic valve implantationAtrial fibrillationCost of hospitalizationCardiac complicationsHospital mortalityEnd pointValve implantationLonger hospital LOSUnderwent Transcatheter Aortic Valve ImplantationPre-existing AFHospital LOSIncidence of AFLonger LOSNationwide Inpatient Sample databaseIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsMixed-effects logistic modelTAVI patients
2017
Hospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Schreiber T, Afonso L, Grines C. Hospital outcomes of transcatheter versus surgical aortic valve replacement in female in the United States. Catheterization And Cardiovascular Interventions 2017, 91: 813-819. PMID: 28990736, DOI: 10.1002/ccd.27362.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisComorbidityCost SavingsCost-Benefit AnalysisDatabases, FactualExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansMiddle AgedPostoperative ComplicationsRisk AssessmentRisk FactorsSex FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementExtracorporeal membrane oxygenationTAVR patientsValve replacementPrimary endpointCardiac surgeryMembrane oxygenationFemale patientsMyocardial infarctionOdds ratioNationwide Inpatient Sample databaseRisk of needAcute kidney injuryNew pacemaker implantationNonfatal myocardial infarctionConcomitant cardiac surgeryPerioperative cardiac arrestMedian hospital costsAcute myocardial infarctionLength of stayPropensity score analysisHospital mortalityNonroutine dischargeComparison of In-Hospital Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Obese (Body Mass Index ≥ 30 Kg/M2) Patients
Ando T, Akintoye E, Trehan N, Telila T, Briasoulis A, Takagi H, Grines C, Afonso L. Comparison of In-Hospital Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Obese (Body Mass Index ≥ 30 Kg/M2) Patients. The American Journal Of Cardiology 2017, 120: 1858-1862. PMID: 28860018, DOI: 10.1016/j.amjcard.2017.07.098.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic ValveAortic Valve StenosisBody Mass IndexComorbidityFemaleFollow-Up StudiesHospital MortalityHumansIncidenceInpatientsMaleObesityPostoperative ComplicationsPrevalencePrognosisPropensity ScoreRisk AssessmentRisk FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationSurgical aortic valve replacementAortic valve replacementTAVI patientsNonroutine dischargeObese patientsValve replacementTranscatheter Aortic Valve Implantation Versus Surgical Aortic Valve ReplacementNationwide Inpatient Sample databaseHigher co-morbidity burdenCertain perioperative complicationsAcute kidney injuryIn-Hospital OutcomesShorter hospital stayAortic valve implantationCo-morbidity burdenMedian hospital costsAcute myocardial infarctionLength of stayCharlson scoreDeyo's modificationHospital mortalityCardiac complicationsHospital stayKidney injuryTrends in Vascular Complications in High-Risk Patients Following Transcatheter Aortic Valve Replacement in the United States
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Grines C, Afonso L. Trends in Vascular Complications in High-Risk Patients Following Transcatheter Aortic Valve Replacement in the United States. The American Journal Of Cardiology 2017, 119: 1433-1437. PMID: 28256249, DOI: 10.1016/j.amjcard.2017.01.028.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Valve StenosisComorbidityDiabetes MellitusFemaleHospital Bed CapacityHospitalsHospitals, RuralHospitals, TeachingHospitals, UrbanHumansMalePeripheral Vascular DiseasesPostoperative ComplicationsRisk FactorsSex FactorsTranscatheter Aortic Valve ReplacementUnited StatesVascular DiseasesConceptsTranscatheter aortic valve replacementHigh-risk groupAortic valve replacementHigh-risk patientsVascular complicationsVC rateValve replacementHigh riskPeripheral vascular disease patientsOverall populationNationwide Inpatient Sample databaseHigh-risk cohortVascular disease patientsContinuous longitudinal monitoringTAVR patientsCenter experienceDiabetes mellitusDisease patientsWorse outcomesInternational ClassificationPatientsSample databaseLongitudinal monitoringSignificant decreaseStatistical significance