2021
Prognostic Implications of Ambulatory N-Terminal Pro-B-Type Natriuretic Peptide Changes in Patients with Continuous-Flow Left Ventricular Assist Devices
Ali A, Akintoye E, Duque E, Kshetri R, Shetty S, Sharma U, Johnson C, Panos A, Briasoulis A, Alvarez P. Prognostic Implications of Ambulatory N-Terminal Pro-B-Type Natriuretic Peptide Changes in Patients with Continuous-Flow Left Ventricular Assist Devices. ASAIO Journal 2021, 68: 524-530. PMID: 34352812, DOI: 10.1097/mat.0000000000001524.Peer-Reviewed Original ResearchConceptsNT-pro BNP concentrationHF hospitalizationBNP concentrationsVentricular assist devicePrognostic implicationsN-terminal pro-B-type natriuretic peptidePro-B-type natriuretic peptideAssist deviceHeart failure hospitalizationNT-pro BNPFailure hospitalizationIndex hospitalizationAdverse eventsLVAD implantationConsecutive patientsAmbulatory patientsNatriuretic peptideRetrospective studyHospitalizationAmbulatory settingPatientsMonth baselineMonthsDeathUnit increase
2020
Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock
Pahuja M, Ranka S, Chehab O, Mishra T, Akintoye E, Adegbala O, Yassin A, Ando T, Thayer K, Shah P, Kimmelstiel C, Salehi P, Kapur N. Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock. Catheterization And Cardiovascular Interventions 2020, 97: 1129-1138. PMID: 32473083, PMCID: PMC8344361, DOI: 10.1002/ccd.29003.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionAcute limb ischemiaLength of stayCardiogenic shockCS-STEMIHospital mortalityVascular complicationsLimb ischemiaClinical outcomesManagement of CSPercutaneous ventricular assist deviceIntra-aortic balloon pumpPercutaneous mechanical circulatory supportRetrospective cohort studyElevation myocardial infarctionMechanical circulatory supportVentricular assist deviceU.S. national databaseTandem HeartMultiorgan failureCohort studyBalloon pumpCommon complicationMembrane oxygenationCirculatory supportTemporal trends and outcomes of patients waiting on left ventricular assist devices and inotropes for heart transplantation
Briasoulis A, Adegbala O, Akintoye E, Alvarez P. Temporal trends and outcomes of patients waiting on left ventricular assist devices and inotropes for heart transplantation. Clinical Transplantation 2020, 34: e13857. PMID: 32167606, DOI: 10.1111/ctr.13857.Peer-Reviewed Original ResearchConceptsLeft ventricular assist deviceRight ventricular assist deviceVentricular assist deviceOutcomes of patientsTime of listingTime of transplantationHeart transplantationAssist deviceOrgan Sharing registryTerms of survivalStatus 1AInotropic therapyLVAD recipientsUnited NetworkWorse outcomesInotropesHigh riskWaiting listPatientsTransplantationLower ratesOutcomesTemporal trendsConfoundersRegistryRelationship between NT-pro Brain Natriuretic Peptide and Filling Pressures in Ambulatory Patients with Left Ventricular Assist Devices and Accuracy to Detect Need for Optimization
Abbas A, Akintoye E, Duque E, Briasoulis A, Alvarez P. Relationship between NT-pro Brain Natriuretic Peptide and Filling Pressures in Ambulatory Patients with Left Ventricular Assist Devices and Accuracy to Detect Need for Optimization. The Journal Of Heart And Lung Transplantation 2020, 39: s344. DOI: 10.1016/j.healun.2020.01.390.Peer-Reviewed Original ResearchPulmonary capillary wedge pressureRight atrial pressureVentricular assist devicePulmonary artery pressureNT-proBNPAmbulatory patientsAssist deviceNatriuretic peptideN-terminal pro-brain natriuretic peptideNT-pro-brain natriuretic peptidePro-brain natriuretic peptideCapillary wedge pressureNT-proBNP levelsRight heart catheterizationMedian NT-proBNPBrain natriuretic peptideBest cutoff valuePg/mLWedge pressureArtery pressureHeart catheterizationAtrial pressurePatient characteristicsHemodynamic optimizationNoninvasive markerThe impact of insurance type on listing status and wait‐list mortality of patients with left ventricular assist devices as bridge to transplantation
Briasoulis A, Akintoye E, Inampudi C, Hammoud A, Alvarez P. The impact of insurance type on listing status and wait‐list mortality of patients with left ventricular assist devices as bridge to transplantation. ESC Heart Failure 2020, 7: 804-810. PMID: 32135039, PMCID: PMC7261523, DOI: 10.1002/ehf2.12655.Peer-Reviewed Original ResearchConceptsLeft ventricular assist deviceInsurance typeVentricular assist deviceTime of listingWaiting listAssist deviceHeart transplantation candidatesOrgan Sharing registryWait-list mortalityRisk regression analysisDifferent insurance typesAdequate health insurance coverageHealth insurance coverageStatus 1APublic health insuranceCumulative incidenceTransplantation candidatesTransplantation ratesUnited NetworkPost-HTMA patientsType of insurancePatientsMortalityCumulative mortality
2019
Gender Differences in Outcomes After Implantation of Left Ventricular Assist Devices
Ahmed A, Adegbala O, Akintoye E, Inampudi C, Ajam M, Yassin A, Olawusi E, Shokr M, Alvarez P, Briasoulis A. Gender Differences in Outcomes After Implantation of Left Ventricular Assist Devices. The Annals Of Thoracic Surgery 2019, 109: 780-786. PMID: 31479642, DOI: 10.1016/j.athoracsur.2019.07.032.Peer-Reviewed Original ResearchConceptsLVAD implantationContinuous-flow LVADVentricular assist device implantationLeft ventricular assist deviceAcute kidney injuryAssist device implantationMost common complicationsExtracorporeal membrane oxygenationMedian hospitalization costNational Inpatient SamplePostoperative cardiac tamponadeLength of stayYears of ageVentricular assist deviceGender-specific differencesHospital mortalityPostoperative thromboembolismCardiac tamponadeHospital outcomesKidney injuryPeriprocedural complicationsPostoperative sepsisCommon complicationInpatient mortalityLVAD placementTrends in the Incidence of In-Hospital Mortality, Cardiogenic Shock, and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005–2014)
Pahuja M, Adegbala O, Mishra T, Akintoye E, Chehab O, Mony S, Singh M, Ando T, Abubaker H, Yassin A, Subahi A, Shokr M, Ranka S, Briasoulis A, Kapur N, Burkhoff D, Afonso L. Trends in the Incidence of In-Hospital Mortality, Cardiogenic Shock, and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005–2014). Journal Of Cardiac Failure 2019, 25: 457-467. PMID: 31035007, DOI: 10.1016/j.cardfail.2019.04.012.Peer-Reviewed Original ResearchConceptsIncidence of CSCardiogenic shockMechanical circulatory supportHospital mortalityMCS devicesPercutaneous ventricular assist deviceNational Inpatient Sample databaseMechanical circulatory support devicesIncidence of myocarditisPercutaneous cardiopulmonary supportCases of myocarditisIn-Hospital MortalityExtracorporeal membrane oxygenationCirculatory support devicesVentricular assist deviceTandem HeartHemodynamic instabilityMultiple comorbiditiesCardiopulmonary supportEndomyocardial biopsyMembrane oxygenationTotal admissionsCirculatory supportPatient mortalityPoor prognosisTemporal Trends and Outcomes of Patients on Left Ventricular Assist Devices and Inotropes at the Time Listing for Heart Transplant
Akintoye E, Briasoulis A, Duque E, Inampudi C, Bhama J, Alvarez P. Temporal Trends and Outcomes of Patients on Left Ventricular Assist Devices and Inotropes at the Time Listing for Heart Transplant. The Journal Of Heart And Lung Transplantation 2019, 38: s347. DOI: 10.1016/j.healun.2019.01.880.Peer-Reviewed Original ResearchLeft ventricular assist deviceOutcomes of patientsTime of listingSub-hazard ratiosVentricular assist deviceInotropic therapyHeart transplantationAssist deviceHigher mean pulmonary arterial pressureMean pulmonary arterial pressureHigh wedge pressurePrior cardiac surgeryOrgan Sharing registryPulmonary arterial pressureTime of transplantNew allocation systemTerms of survivalWedge pressureLVAD patientsMethods PatientsArterial pressureCardiac surgeryHeart transplantPrimary outcomeLVAD support
2018
Clinical Impact of Diabetes Mellitus on Short-Term Outcomes andIn-Hospital Mortality of Cardiac Mechanical Support with Left Ventricular Assist Device (LVAD): A Retrospective Study from a National Database
Yassin A, Subahi A, Adegbala O, Abubakar H, Akintoye E, Ahmed A, Ismail A, Elhag A, Kambal A, Alade A, Shokr M, Weinberger J, Levine D, Afonso L. Clinical Impact of Diabetes Mellitus on Short-Term Outcomes andIn-Hospital Mortality of Cardiac Mechanical Support with Left Ventricular Assist Device (LVAD): A Retrospective Study from a National Database. Cardiovascular Revascularization Medicine 2018, 20: 883-886. PMID: 30578171, DOI: 10.1016/j.carrev.2018.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedDatabases, FactualDiabetes MellitusFemaleHeart FailureHeart-Assist DevicesHospital MortalityHumansMaleMiddle AgedProsthesis DesignProsthesis ImplantationRecovery of FunctionRegistriesRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVentricular Dysfunction, LeftVentricular Function, LeftConceptsLeft ventricular assist deviceCardiac mechanical supportDiabetes mellitusCost of hospitalizationCardiac supportVentricular assist deviceHospital mortalityDiabetic patientsHeart failureClinical impactMultivariable logistic regression model analysisAssist deviceStage D heart failureAdvanced congestive heart failureNational Inpatient Sample databasePost-LVAD complicationsShort-term complicationsCongestive heart failureLogistic regression model analysisHospital-level characteristicsImpact of diabetesRegression model analysisInpatient mortalityLVAD implantationSecondary outcomesTrends in Utilization, Mortality, Major Complications, and Cost After Left Ventricular Assist Device Implantation in the United States (2009 to 2014)
Briasoulis A, Inampudi C, Akintoye E, Adegbala O, Alvarez P, Bhama J. Trends in Utilization, Mortality, Major Complications, and Cost After Left Ventricular Assist Device Implantation in the United States (2009 to 2014). The American Journal Of Cardiology 2018, 121: 1214-1218. PMID: 29525059, DOI: 10.1016/j.amjcard.2018.01.041.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultAgedCardiac TamponadeDatabases, FactualFemaleHealth Care CostsHeart FailureHeart-Assist DevicesHospital CostsHospital MortalityHumansLength of StayLogistic ModelsMaleMiddle AgedMortalityMyocardial InfarctionPatient DischargePostoperative ComplicationsPostoperative HemorrhageProsthesis ImplantationRenal DialysisRespiratory Tract DiseasesStrokeSurgical Wound DehiscenceSurgical Wound InfectionUnited StatesConceptsLength of stayMajor complicationsHospital mortalityLeft ventricular assist device (LVAD) implantsVentricular assist device implantsVentricular assist device implantationAssist device implantationHospital mortality rateNational Inpatient SampleTime of dischargeCost of hospitalizationSignificant decreaseAnnual national estimatesVentricular assist deviceHospital complicationsMajor bleedingCardiac tamponadeRespiratory complicationsAdult patientsIschemic strokePostoperative infectionCF-LVADCF-LVADsDevice implantationInpatient Sample