2020
Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock
Pahuja M, Ranka S, Chehab O, Mishra T, Akintoye E, Adegbala O, Yassin A, Ando T, Thayer K, Shah P, Kimmelstiel C, Salehi P, Kapur N. Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock. Catheterization And Cardiovascular Interventions 2020, 97: 1129-1138. PMID: 32473083, PMCID: PMC8344361, DOI: 10.1002/ccd.29003.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionAcute limb ischemiaLength of stayCardiogenic shockCS-STEMIHospital mortalityVascular complicationsLimb ischemiaClinical outcomesManagement of CSPercutaneous ventricular assist deviceIntra-aortic balloon pumpPercutaneous mechanical circulatory supportRetrospective cohort studyElevation myocardial infarctionMechanical circulatory supportVentricular assist deviceU.S. national databaseTandem HeartMultiorgan failureCohort studyBalloon pumpCommon complicationMembrane oxygenationCirculatory support
2018
Comparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement
Abubakar H, Subahi A, Adegbala O, Yassin A, Akintoye E, Abdulrahman A, Ahmed A, Alade A, Pahuja M, Afonso L. Comparison of In-Hospital Outcomes of Patients With-Versus-Without Ischemic Cardiomyopathy Undergoing Left Ventricular Assist Device Placement. The American Journal Of Cardiology 2018, 123: 414-418. PMID: 30545482, DOI: 10.1016/j.amjcard.2018.10.039.Peer-Reviewed Original ResearchConceptsVentricular assist device placementPostoperative myocardial infarctionLength of stayHospital mortalityVascular complicationsLVAD placementMyocardial infarctionEnd pointLeft ventricular assist device placementNationwide Inpatient Sample databaseST-segment myocardial infarctionDevice placementPeriprocedural vascular complicationsHeart failure etiologyIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsCost of hospitalizationHemorrhage requiring transfusionMixed-effects logistic modelHospital outcomesFailure etiologyIschemic cardiomyopathyOutcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation
Yassin A, Subahi A, Abubakar H, Akintoye E, Alhusain R, Adegbala O, Ahmed A, Elmoughrabi A, Subahi E, Pahuja M, Sahlieh A, Elder M, Kaki A, Schreiber T, Mohamad T. Outcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 455-460. PMID: 30041889, DOI: 10.1016/j.amjcard.2018.04.013.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationAortic valve implantationLiver cirrhosisCirrhotic patientsValve implantationUnderwent Transcatheter Aortic Valve ImplantationNational Inpatient Sample databasePropensity score-matched analysisNonroutine hospital dischargeSevere aortic stenosisAortic valve replacementReasonable therapeutic optionCost of hospitalizationHospital mortalityHospital stayVascular complicationsHospital dischargeInpatient mortalitySecondary outcomesValve replacementAortic stenosisPacemaker implantationPrimary outcomeProcedural complicationsClinical outcomesClinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database)
Ando T, Akintoye E, Holmes A, Briasoulis A, Pahuja M, Takagi H, Schreiber T, Grines C, Afonso L. Clinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database). The American Journal Of Cardiology 2018, 122: 279-283. PMID: 29880287, DOI: 10.1016/j.amjcard.2018.03.356.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAortic ValveAortic Valve StenosisCause of DeathFemaleFollow-Up StudiesHospital MortalityHumansIncidenceInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesYoung AdultConceptsSurgical aortic valve replacementTranscatheter aortic valve implantationAortic valve replacementShorter hospital stayAortic valve implantationHospital mortalityHospital stayValve replacementValve implantationNational Inpatient Sample databaseSafe alternativeAcute kidney injuryOlder patient populationClinical end pointsAcute myocardial infarctionPropensity score analysisYears of agePostprocedure strokeKidney injuryValve surgeryVascular complicationsMajor complicationsPacemaker implantationPatient populationMyocardial infarction
2017
Trends in Vascular Complications in High-Risk Patients Following Transcatheter Aortic Valve Replacement in the United States
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Grines C, Afonso L. Trends in Vascular Complications in High-Risk Patients Following Transcatheter Aortic Valve Replacement in the United States. The American Journal Of Cardiology 2017, 119: 1433-1437. PMID: 28256249, DOI: 10.1016/j.amjcard.2017.01.028.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Valve StenosisComorbidityDiabetes MellitusFemaleHospital Bed CapacityHospitalsHospitals, RuralHospitals, TeachingHospitals, UrbanHumansMalePeripheral Vascular DiseasesPostoperative ComplicationsRisk FactorsSex FactorsTranscatheter Aortic Valve ReplacementUnited StatesVascular DiseasesConceptsTranscatheter aortic valve replacementHigh-risk groupAortic valve replacementHigh-risk patientsVascular complicationsVC rateValve replacementHigh riskPeripheral vascular disease patientsOverall populationNationwide Inpatient Sample databaseHigh-risk cohortVascular disease patientsContinuous longitudinal monitoringTAVR patientsCenter experienceDiabetes mellitusDisease patientsWorse outcomesInternational ClassificationPatientsSample databaseLongitudinal monitoringSignificant decreaseStatistical significanceComparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample)
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Slovut D, Schreiber T, Grines C, Afonso L. Comparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample). The American Journal Of Cardiology 2017, 119: 1250-1254. PMID: 28219665, DOI: 10.1016/j.amjcard.2016.12.026.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overBlood TransfusionDatabases, FactualDiabetes MellitusExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansLength of StayMaleMyocardial InfarctionPacemaker, ArtificialPostoperative ComplicationsSepsisTranscatheter Aortic Valve ReplacementUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementTAVR patientsValve replacementDM patientsHospital outcomesOdds ratioOutcomes of TAVRTranscatheter Versus Surgical Aortic Valve ReplacementNationwide Inpatient Sample databasePrimary end pointNew pacemaker implantationDiabetes mellitus patientsMean hospitalization costAcute myocardial infarctionLength of staySAVR patientsSAVR proceduresCardiac complicationsCause mortalityPerioperative complicationsPostoperative sepsisRespiratory complicationsVascular complications