2020
Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation
Akintoye E, Ando T, Sandio A, Adegbala O, Salih M, Zubairu J, Oseni A, Sistla P, Alqasrawi M, Egbe A, Mentias A, Afonso L, Briasoulis A, Panaich S, Desai M. Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2020, 126: 73-81. PMID: 32336533, DOI: 10.1016/j.amjcard.2020.03.038.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisAortic valve replacementNational Inpatient SampleTAVI eraAortic stenosisMean annual changeValve replacementFavorable short-term outcomesTranscatheter aortic valve replacementTranscatheter aortic valve implantationRate of AVRAcute kidney injuryRate of strokeAortic valve implantationShort-term outcomesRisk-adjusted ratesHospital mortalityPre-TAVIHospital outcomesKidney injuryHome dischargeHospital dischargePacemaker implantationValve implantationMedian length
2019
Trends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database
Egbe A, Vallabhajosyula S, Akintoye E, Connolly H. Trends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database. Canadian Journal Of Cardiology 2019, 35: 721-726. PMID: 31151707, DOI: 10.1016/j.cjca.2019.02.006.Peer-Reviewed Original ResearchConceptsHealth care resource utilizationTetralogy of FallotProsthetic valve implantationNational Inpatient SampleCongenital heart diseaseHospital mortalityValve implantationInfective endocarditisHeart diseaseRisk factorsTOF patientsInflation-adjusted hospitalization costsNational Inpatient Sample databaseCyanotic congenital heart diseaseIncidence of endocarditisLength of stayPacemaker/defibrillatorLow socioeconomic classPopulation-based riskHospital dischargeSecondary outcomesPrimary outcomeHospitalization costsBlack raceInpatient SamplePredictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Briasoulis A, Telila T, Takagi H, Grines C, Schreiber T, Bhatt D, Afonso L. Predictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2019, 123: 1142-1148. PMID: 30658917, DOI: 10.1016/j.amjcard.2018.12.044.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisDatabases, FactualFemaleHospital CostsHospital MortalityHospitalizationHumansIncidenceInpatientsMalePatient Acceptance of Health CarePostoperative ComplicationsPropensity ScoreRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseHigh-cost groupHigher hospitalization costsAortic valve implantationHospitalization costsValve implantationHospital costsSample databaseSurgical aortic valve replacementCost groupsHigher co-morbidity burdenAcute kidney injuryAcute respiratory failureAortic valve replacementPeripheral vascular diseaseCo-morbidity burdenCost of hospitalizationLength of stayMultivariable regression analysisLow-cost groupHigh incremental costPost-TAVITAVI hospitalizationsCardiogenic shock
2018
Incidence, Predictors, and In-Hospital Outcomes of Transcatheter Aortic Valve Implantation After Nonelective Admission in Comparison With Elective Admission: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Shokr M, Briasoulis A, Takagi H, Grines C, Afonso L, Schreiber T. Incidence, Predictors, and In-Hospital Outcomes of Transcatheter Aortic Valve Implantation After Nonelective Admission in Comparison With Elective Admission: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2018, 123: 100-107. PMID: 30360892, DOI: 10.1016/j.amjcard.2018.09.023.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseNonelective admissionsPropensity-matched cohortAortic valve implantationHospital mortalityValve implantationElective admissionsOutcomes of TAVITransarterial transcatheter aortic valve implantationSample databaseHigher adverse outcomesPulmonary circulation disordersAcute kidney injuryHealth resource utilizationIn-Hospital OutcomesChronic kidney diseaseIndependent risk factorCongestive heart failureHigh-risk cohortAcute myocardial infarctionCardiogenic shockHospital lengthKidney injuryRespiratory failureFailure to Rescue, Hospital Volume, and In-Hospital Mortality After Transcatheter Aortic Valve Implantation
Ando T, Adegbala O, Villablanca P, Shokr M, Akintoye E, Briasoulis A, Takagi H, Schreiber T, Grines C, Afonso L. Failure to Rescue, Hospital Volume, and In-Hospital Mortality After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 828-832. PMID: 30064862, DOI: 10.1016/j.amjcard.2018.05.020.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationMajor perioperative complicationsAortic valve implantationVolume hospitalsHospital volumePatient mortalityPerioperative complicationsValve implantationTransarterial transcatheter aortic valve implantationNationwide Inpatient Sample databaseCo-morbidity indexGreater hospital volumeIn-Hospital MortalityPatient mortality ratesPercentage of womenHospital mortalityMajor complicationsTAVI procedureHighest quintileMean ageLowest quintileAdjusted ratesMortality rateFourth quintileDifferent hospitalsComparison of Hospital Outcomes of Transcatheter AorticValve Implantation With Versus Without Hypothyroidism
Subahi A, Yassin A, Adegbala O, Akintoye E, Abubakar H, Elmoghrabi A, Ibrahim W, Ajam M, Pahuja M, Weinberger J, Levine D, Afonso L. Comparison of Hospital Outcomes of Transcatheter AorticValve Implantation With Versus Without Hypothyroidism. The American Journal Of Cardiology 2018, 122: 838-843. PMID: 30037424, DOI: 10.1016/j.amjcard.2018.05.025.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationHypothyroid patientsImpact of hypothyroidismHospital outcomesSevere symptomatic aortic stenosisNational Inpatient Sample databasePropensity score-matched analysisSymptomatic aortic stenosisAdditional randomized trialsAortic valve implantationCost of hospitalizationHemorrhage requiring transfusionEffect of hypothyroidismHospital mortalityTAVR outcomesHospital stayInpatient mortalityPostprocedural complicationsSecondary outcomesValve implantationAortic stenosisBlood transfusionPrimary outcomeClinical outcomesRandomized trialsOutcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation
Yassin A, Subahi A, Abubakar H, Akintoye E, Alhusain R, Adegbala O, Ahmed A, Elmoughrabi A, Subahi E, Pahuja M, Sahlieh A, Elder M, Kaki A, Schreiber T, Mohamad T. Outcomes and Effects of Hepatic Cirrhosis in Patients Who Underwent Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 455-460. PMID: 30041889, DOI: 10.1016/j.amjcard.2018.04.013.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationAortic valve implantationLiver cirrhosisCirrhotic patientsValve implantationUnderwent Transcatheter Aortic Valve ImplantationNational Inpatient Sample databasePropensity score-matched analysisNonroutine hospital dischargeSevere aortic stenosisAortic valve replacementReasonable therapeutic optionCost of hospitalizationHospital mortalityHospital stayVascular complicationsHospital dischargeInpatient mortalitySecondary outcomesValve replacementAortic stenosisPacemaker implantationPrimary outcomeProcedural complicationsClinical outcomesClinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database)
Ando T, Akintoye E, Holmes A, Briasoulis A, Pahuja M, Takagi H, Schreiber T, Grines C, Afonso L. Clinical End Points of Transcatheter Aortic Valve Implantation Compared With Surgical Aortic Valve Replacement in Patients <65 Years of Age (From the National Inpatient Sample Database). The American Journal Of Cardiology 2018, 122: 279-283. PMID: 29880287, DOI: 10.1016/j.amjcard.2018.03.356.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAortic ValveAortic Valve StenosisCause of DeathFemaleFollow-Up StudiesHospital MortalityHumansIncidenceInpatientsLength of StayMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRegistriesRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesYoung AdultConceptsSurgical aortic valve replacementTranscatheter aortic valve implantationAortic valve replacementShorter hospital stayAortic valve implantationHospital mortalityHospital stayValve replacementValve implantationNational Inpatient Sample databaseSafe alternativeAcute kidney injuryOlder patient populationClinical end pointsAcute myocardial infarctionPropensity score analysisYears of agePostprocedure strokeKidney injuryValve surgeryVascular complicationsMajor complicationsPacemaker implantationPatient populationMyocardial infarctionFinancial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database)
Abubakar H, Yassin A, Akintoye E, Bakhit K, Pahuja M, Shokr M, Lieberman R, Afonso L. Financial Implications and Impact of Pre-existing Atrial Fibrillation on In-Hospital Outcomes in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the National Inpatient Database). The American Journal Of Cardiology 2018, 121: 1587-1592. PMID: 29622287, DOI: 10.1016/j.amjcard.2018.02.052.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Valve StenosisArrhythmias, CardiacAtrial FibrillationCardiac Pacing, ArtificialCardiac TamponadeComorbidityDatabases, FactualFemaleHeart ArrestHeart FailureHospital CostsHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMyocardial InfarctionPacemaker, ArtificialPericardial EffusionPostoperative ComplicationsPostoperative HemorrhageStrokeTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationPre-existing atrial fibrillationLength of stayPeriprocedural cardiac complicationsAortic valve implantationAtrial fibrillationCost of hospitalizationCardiac complicationsHospital mortalityEnd pointValve implantationLonger hospital LOSUnderwent Transcatheter Aortic Valve ImplantationPre-existing AFHospital LOSIncidence of AFLonger LOSNationwide Inpatient Sample databaseIn-Hospital OutcomesPrimary end pointSecondary end pointsClinical end pointsHospital-level characteristicsMixed-effects logistic modelTAVI patients
2017
Early Prosthetic Valve Dysfunction Due to Bioprosthetic Valve Thrombosis The Role of Echocardiography
Egbe A, Pislaru S, Ali M, Khan A, Boler A, Schaff H, Akintoye E, Connolly H, Nkomo V, Pellikka P. Early Prosthetic Valve Dysfunction Due to Bioprosthetic Valve Thrombosis The Role of Echocardiography. JACC Cardiovascular Imaging 2017, 11: 951-958. PMID: 29055629, DOI: 10.1016/j.jcmg.2017.06.022.Peer-Reviewed Original ResearchConceptsProsthetic valve dysfunctionBioprosthetic valve thrombosisTransthoracic echocardiographyPVD diagnosisValve thrombosisValve implantationRetrospective case-control studyAcute disease processPatients ages 61Role of echocardiographyRoutine transthoracic echocardiographyCase-control studyMen 61Symptomatic deteriorationMost patientsValve dysfunctionAppropriate therapyInitial diagnosisSF patientsBioprosthetic valvesTimely diagnosisPatient's conditionBaseline gradientAge 61Disease processTranscatheter aortic valve implantation in the United States: Predictors of early hospital discharge
Mallikethi‐Reddy S, Akintoye E, Telila T, Sudhakar R, Jagadeesh K, Briasoulis A, Rubenfire M, Afonso L, Grines C. Transcatheter aortic valve implantation in the United States: Predictors of early hospital discharge. Journal Of Interventional Cardiology 2017, 30: 149-155. PMID: 28247569, DOI: 10.1111/joic.12373.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationEarly hospital dischargeAortic valve implantationEarly dischargeDischarge cohortPost-TAVIAortic valvuloplastyHospital dischargeBlood transfusionValve implantationPermanent pacemakerNationwide Inpatient Sample databaseMechanical circulatory support devicesAcute kidney injuryEarly discharge cohortTransfemoral TAVI approachHigher hospitalization costsMechanical circulatory supportCost of hospitalizationOverall mean ageHealthcare Utilization ProjectCirculatory support devicesHospital outcomesKidney injuryRenal failure