Rilonacept for the treatment of recurrent pericarditis
Fava A, Reyaldeen R, Presti S, Goyal A, Akintoye E, Hughes D, Klein A. Rilonacept for the treatment of recurrent pericarditis. Expert Opinion On Biological Therapy 2022, 22: 7-16. PMID: 34757872, DOI: 10.1080/14712598.2022.2005024.Peer-Reviewed Original ResearchConceptsRecurrent pericarditisC-reactive proteinClinical trialsUpper respiratory tract infectionSafety of rilonaceptCommon adverse eventsRespiratory tract infectionsAvailable clinical trialsInjection site reactionsRapid clinical responseValuable therapeutic optionGood safety profilePromising new therapyIL-1β signalingDimeric fusion proteinGlucocorticoid-dependent diseasesAdverse eventsClinical responseTherapy durationTract infectionsSuccessful weaningRecurrence rateSafety profileTherapeutic optionsFuture trials