2023
Prognostic Utility of Left Atrial Strain to Predict Thrombotic Events and Mortality in Amyloid Cardiomyopathy
Akintoye E, Majid M, Klein A, Hanna M. Prognostic Utility of Left Atrial Strain to Predict Thrombotic Events and Mortality in Amyloid Cardiomyopathy. JACC Cardiovascular Imaging 2023, 16: 1371-1383. PMID: 37940322, DOI: 10.1016/j.jcmg.2023.01.015.Peer-Reviewed Original ResearchConceptsThrombotic eventsAmyloid cardiomyopathyAtrial fibrillationLA contractileLA strainLA contractile strainModest discriminatory abilityPrognostic staging systemRisk stratification toolLeft Atrial StrainHigh thrombotic riskAtrial strainPrognostic utilityStratification toolPrognostic valueC-statisticRespective HRsStaging systemThrombotic riskACM patientsSD decreaseAF casesPredictive valuePatientsDiscriminatory ability
2022
Quantitative Echocardiographic Assessment and Optimal Criteria for Early Intervention in Asymptomatic Tricuspid Regurgitation
Akintoye E, Wang T, Nakhla M, Ali A, Fava A, Akyuz K, Popovic Z, Pettersson G, Gillinov A, Xu B, Griffin B, Desai M. Quantitative Echocardiographic Assessment and Optimal Criteria for Early Intervention in Asymptomatic Tricuspid Regurgitation. JACC Cardiovascular Imaging 2022, 16: 13-24. PMID: 36274042, DOI: 10.1016/j.jcmg.2022.08.004.Peer-Reviewed Original ResearchConceptsTricuspid regurgitationMedian survival timeRisk factorsAsymptomatic patientsEchocardiographic parametersSurvival timeEarly interventionOptimal timingRight heart parametersSymptomatic tricuspid regurgitationSignificant tricuspid regurgitationFree wall strainHigh operative mortalitySex-matched cohortQuantitative echocardiographic assessmentKey prognostic markersCause mortalityOperative mortalityTR patientsEchocardiographic assessmentLate presentationPoor outcomePrognostic utilityPrognostic valuePrognostic marker
2021
Prognostic Utility of Risk Enhancers and Coronary Artery Calcium Score Recommended in the 2018 ACC/AHA Multisociety Cholesterol Treatment Guidelines Over the Pooled Cohort Equation: Insights From 3 Large Prospective Cohorts
Akintoye E, Afonso L, Jayanna M, Bao W, Briasoulis A, Robinson J. Prognostic Utility of Risk Enhancers and Coronary Artery Calcium Score Recommended in the 2018 ACC/AHA Multisociety Cholesterol Treatment Guidelines Over the Pooled Cohort Equation: Insights From 3 Large Prospective Cohorts. Journal Of The American Heart Association 2021, 10: e019589. PMID: 34092110, PMCID: PMC8477885, DOI: 10.1161/jaha.120.019589.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmerican Heart AssociationBiomarkersCardiovascular DiseasesCholesterolClinical Decision-MakingCoronary Artery DiseaseDecision Support TechniquesDyslipidemiasFemaleHeart Disease Risk FactorsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIncidenceMaleMiddle AgedPractice Guidelines as TopicPredictive Value of TestsPrimary PreventionPrognosisRisk AssessmentTime FactorsUnited StatesVascular CalcificationConceptsPooled Cohort EquationsCoronary artery calcium scoreCholesterol treatment guidelinesArtery calcium scoreAtherosclerotic cardiovascular diseaseCohort EquationsRisk enhancersCalcium scoreTreatment guidelinesCardiovascular diseaseAmerican Heart Association/American CollegeAtherosclerotic cardiovascular disease eventsBackground Limited dataIntermediate-risk participantsIntermediate-risk patientsCardiovascular disease eventsLarge prospective cohortIncremental valueNet reclassification indexStatin therapyCAC testingProspective cohortPrognostic utilityC-statisticReclassification index
2020
PROGNOSTIC UTILITY OF RISK ENHANCERS RECOMMENDED IN THE 2018 ACC/AHA CHOLESTEROL TREATMENT GUIDELINES OVER THE POOLED COHORT EQUATION: INSIGHTS FROM 3 LARGE PROSPECTIVE COHORTS
Akintoye E, Briasoulis A, Robinson J. PROGNOSTIC UTILITY OF RISK ENHANCERS RECOMMENDED IN THE 2018 ACC/AHA CHOLESTEROL TREATMENT GUIDELINES OVER THE POOLED COHORT EQUATION: INSIGHTS FROM 3 LARGE PROSPECTIVE COHORTS. Journal Of The American College Of Cardiology 2020, 75: 1833. DOI: 10.1016/s0735-1097(20)32460-8.Peer-Reviewed Original Research
2018
Racial/ethnic differences in the prognostic utility of left ventricular mass index for incident cardiovascular disease
Akintoye E, Mahmoud K, Shokr M, Sandio A, Mallikethi‐Reddy S, Sheikh M, Adegbala O, Egbe A, Briasoulis A, Afonso L. Racial/ethnic differences in the prognostic utility of left ventricular mass index for incident cardiovascular disease. Clinical Cardiology 2018, 41: 502-509. PMID: 29663526, PMCID: PMC6490106, DOI: 10.1002/clc.22914.Peer-Reviewed Original ResearchMeSH KeywordsAgedAsianBlack or African AmericanCardiovascular DiseasesComorbidityDatabases, FactualDisease ProgressionFemaleHispanic or LatinoHumansHypertrophy, Left VentricularIncidenceMagnetic Resonance Imaging, CineMaleMiddle AgedPredictive Value of TestsPrognosisProportional Hazards ModelsRacial GroupsRisk FactorsTime FactorsUnited StatesVentricular Function, LeftVentricular RemodelingWhite PeopleConceptsLeft ventricular mass indexLeft ventricular hypertrophyNon-Hispanic whitesVentricular mass indexCVD eventsIncident CVDMass indexPrognostic utilityEthnic differencesFuture cardiovascular disease eventsOptimal cutpointCardiovascular disease eventsFuture CVD eventsIncident cardiovascular diseaseRisk stratification strategiesIncident cardiovascular outcomesMulti-Ethnic StudyRace/ethnicityCardiovascular outcomesLVMI valuesVentricular hypertrophyCardiovascular diseaseDisease eventsCox modelStratification strategies