2024
Long-Term Outcomes of Patients With Apical Hypertrophic Cardiomyopathy Utilizing a New Risk Score
Hajj-Ali A, Gaballa A, Akintoye E, Jadam S, Ramchand J, Xu B, Ospina S, Thamilarasan M, Smedira N, Popovic Z, Desai M. Long-Term Outcomes of Patients With Apical Hypertrophic Cardiomyopathy Utilizing a New Risk Score. JACC Advances 2024, 3: 101235. DOI: 10.1016/j.jacadv.2024.101235.Peer-Reviewed Original ResearchApical hypertrophic cardiomyopathyRight ventricular systolic pressureLeft atrial volume indexAtrial volume indexVentricular systolic pressureRisk scoreApical aneurysmEnd pointsHypertrophic cardiomyopathyMean left ventricle ejection fractionSystolic pressureLong-term outcomes of patientsApical hypertrophic cardiomyopathy patientsVolume indexBaseline cardiac magnetic resonanceComposite primary end pointPrimary end pointOutcomes of patientsVentricle ejection fractionDelayed gadolinium enhancementCardiac magnetic resonanceComposite end pointLong-term outcomesComposite event rateLeft ventricle apex
2022
Trends and Outcomes of Patients With Amyloid Cardiomyopathy Listed for Heart Transplantation
Akintoye E, Salih M, Aje K, Alvarez P, Sellke F, Briasoulis A, Dorbala S. Trends and Outcomes of Patients With Amyloid Cardiomyopathy Listed for Heart Transplantation. Canadian Journal Of Cardiology 2022, 38: 1263-1270. PMID: 35525397, DOI: 10.1016/j.cjca.2022.04.023.Peer-Reviewed Original ResearchConceptsHeart transplantGraft survivalAmyloid cardiomyopathyWaitlist mortalityHeart transplantationRisk factorsSingle-organ heart transplantsStudy periodHeart transplant waitlistUnderwent heart transplantWorse graft survivalGraft survival ratesOutcomes of patientsPropensity-matched cohortOrgan Sharing databaseHigher waitlist mortalityNumber of patientsNumber of transplantsAmyloid recurrenceAdult patientsGraft failureRenal failureIndependent predictorsSharing databaseUnited Network
2021
Outcomes of diabetic patients with end-stage heart failure listed for heart transplantation: a propensity-matched analysis
Akintoye E, Alvarez P, Briasoulis A. Outcomes of diabetic patients with end-stage heart failure listed for heart transplantation: a propensity-matched analysis. European Heart Journal 2021, 42: ehab724.0967. DOI: 10.1093/eurheartj/ehab724.0967.Peer-Reviewed Original ResearchHeart transplantWaitlist mortalityPost-transplant graft survivalEnd-stage heart failureOutcomes of patientsPropensity-matched cohortHeart failure patientsGraft survivalAdult patientsFailure patientsGraft failureDiabetic patientsHeart failureDiabetic cohortPoor outcomeUnited NetworkRisk factorsOrgan SharingPatientsTransplantStudy periodCohortMortalityOutcomesRisk
2020
State-Level Variation in Waitlist Mortality and Transplant Outcomes Among Patients Listed for Heart Transplantation in the US From 2011 to 2016
Akintoye E, Shin D, Alvarez P, Briasoulis A. State-Level Variation in Waitlist Mortality and Transplant Outcomes Among Patients Listed for Heart Transplantation in the US From 2011 to 2016. JAMA Network Open 2020, 3: e2028459. PMID: 33295970, PMCID: PMC7726636, DOI: 10.1001/jamanetworkopen.2020.28459.Peer-Reviewed Original ResearchConceptsHeart transplantationGraft survivalWaitlist mortalityStatus 1AAdult patientsTransplant ratesSignificant state-level variationNationwide retrospective cohort studyAdult heart transplantationOutcomes of patientsRetrospective cohort studyMultivariable-adjusted modelsOrgan Sharing databaseRate of transplantRate of deathState-level variationRisk-adjustment modelsTransplant outcomesCohort studySharing databaseMedian timeScientific RegistryUnited NetworkLowest quartileOutcome measuresCharacteristics and Outcomes of Patients Undergoing Combined Organ Transplantation (from the United Network for Organ Sharing)
Briasoulis A, Akintoye E, Kuno T, Alvarez P. Characteristics and Outcomes of Patients Undergoing Combined Organ Transplantation (from the United Network for Organ Sharing). The American Journal Of Cardiology 2020, 129: 42-45. PMID: 32540168, DOI: 10.1016/j.amjcard.2020.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlack or African AmericanCardiomyopathy, DilatedCardiomyopathy, RestrictiveFemaleGraft RejectionHeart Defects, CongenitalHeart FailureHeart TransplantationHeart-Lung TransplantationHispanic or LatinoHumansKidney DiseasesKidney TransplantationLiver DiseasesLiver TransplantationLung DiseasesMaleMiddle AgedMortalityProportional Hazards ModelsRegistriesReoperationSurvival RateWhite PeopleConceptsHeart-liver transplantPrimary heart transplantationLong-term survivalHeart transplantationOrgan transplantsStage D heart failureD heart failureOutcomes of patientsOrgan Sharing registryLong-term outcomesCongenital heart diseaseAdult patientsMedian survivalHeart failureTransplantation ratesUnited NetworkList timeHeart diseaseOperative characteristicsOrgan transplantationSurvival analysisPatientsTransplantInverse probabilityStudy periodTemporal trends and outcomes of patients waiting on left ventricular assist devices and inotropes for heart transplantation
Briasoulis A, Adegbala O, Akintoye E, Alvarez P. Temporal trends and outcomes of patients waiting on left ventricular assist devices and inotropes for heart transplantation. Clinical Transplantation 2020, 34: e13857. PMID: 32167606, DOI: 10.1111/ctr.13857.Peer-Reviewed Original ResearchConceptsLeft ventricular assist deviceRight ventricular assist deviceVentricular assist deviceOutcomes of patientsTime of listingTime of transplantationHeart transplantationAssist deviceOrgan Sharing registryTerms of survivalStatus 1AInotropic therapyLVAD recipientsUnited NetworkWorse outcomesInotropesHigh riskWaiting listPatientsTransplantationLower ratesOutcomesTemporal trendsConfoundersRegistryTemporal Trends and Outcomes of Patients Undergoing Combined Organ Transplantation: Insights from the United Network for Organ Sharing (UNOS)
Briasoulis A, Akintoye E, Alvarez P. Temporal Trends and Outcomes of Patients Undergoing Combined Organ Transplantation: Insights from the United Network for Organ Sharing (UNOS). The Journal Of Heart And Lung Transplantation 2020, 39: s167-s168. DOI: 10.1016/j.healun.2020.01.1126.Peer-Reviewed Original ResearchHeart-liver transplantPrimary heart transplantationLong-term survivalHeart transplantationUnited NetworkOrgan transplantsStage D heart failureD heart failureMethods Adult patientsOutcomes of patientsOrgan Sharing registryLong-term outcomesCongenital heart diseaseAdult patientsMedian survivalHeart failureTransplantation ratesList timeHeart diseaseOperative characteristicsOrgan transplantationOrgan SharingSurvival analysisPatientsTransplant
2019
Temporal Trends and Outcomes of Patients on Left Ventricular Assist Devices and Inotropes at the Time Listing for Heart Transplant
Akintoye E, Briasoulis A, Duque E, Inampudi C, Bhama J, Alvarez P. Temporal Trends and Outcomes of Patients on Left Ventricular Assist Devices and Inotropes at the Time Listing for Heart Transplant. The Journal Of Heart And Lung Transplantation 2019, 38: s347. DOI: 10.1016/j.healun.2019.01.880.Peer-Reviewed Original ResearchLeft ventricular assist deviceOutcomes of patientsTime of listingSub-hazard ratiosVentricular assist deviceInotropic therapyHeart transplantationAssist deviceHigher mean pulmonary arterial pressureMean pulmonary arterial pressureHigh wedge pressurePrior cardiac surgeryOrgan Sharing registryPulmonary arterial pressureTime of transplantNew allocation systemTerms of survivalWedge pressureLVAD patientsMethods PatientsArterial pressureCardiac surgeryHeart transplantPrimary outcomeLVAD supportCharacteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis
Inampudi C, Adegbala O, Akintoye E, Alvarez P, Briasoulis A. Characteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis. The Journal Of Heart And Lung Transplantation 2019, 38: s63. DOI: 10.1016/j.healun.2019.01.141.Peer-Reviewed Original ResearchLength of stayCardiogenic shockOutcomes of patientsHospital mortalityAcute Kidney Injury Requiring HemodialysisPre-existing chronic kidney diseasePropensity score-matched groupsHigher comorbidity burdenAcute kidney injuryChronic kidney diseaseRenal replacement therapyHospital-level characteristicsRenal venous pressureNational Inpatient SampleComorbidity burdenHospital morbidityHospital outcomesKidney injuryElixhauser scoreRenal functionBiventricular functionDiabetes mellitusRenal perfusionVenous pressureHospitalization costsCharacteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury
Adegbala O, Inampudi C, Adejumo A, Otuonye G, Akintoye E, Elsayed R, Williams K, Alvarez P, Afonso L, Briasoulis A. Characteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury. The American Journal Of Cardiology 2019, 123: 1816-1821. PMID: 30967283, DOI: 10.1016/j.amjcard.2019.02.038.Peer-Reviewed Original ResearchConceptsLength of stayAcute kidney injuryCardiogenic shockOutcomes of patientsHospital mortalityKidney injuryTemporary mechanical supportCause of CSPropensity score-matched groupsST-elevation myocardial infarctionMechanical circulatory support devicesHigher comorbidity burdenRenal replacement therapyElevation myocardial infarctionHospital-level characteristicsRenal venous pressureNational Inpatient SampleCirculatory support devicesComorbidity burdenHospital morbidityHospital outcomesRenal functionBiventricular functionRenal perfusionVenous pressureCHARACTERISTICS AND OUTCOMES OF PATIENTS WITH CARDIOGENIC SHOCK COMPLICATED BY ACUTE KIDNEY INJURY REQUIRING HEMODIALYSIS
Adegbala O, Inampudi C, Akintoye E, Elsayed R, Jara C, Williams K, Voruganti D, Afonso L, Briasoulis A. CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH CARDIOGENIC SHOCK COMPLICATED BY ACUTE KIDNEY INJURY REQUIRING HEMODIALYSIS. Journal Of The American College Of Cardiology 2019, 73: 1393. DOI: 10.1016/s0735-1097(19)32000-5.Peer-Reviewed Original Research
2017
Incidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Transcatheter Aortic Valve Replacement
Telila T, Akintoye E, Ando T, Merid O, Mallikethi-Reddy S, Briasoulis A, Grines C, Afonso L. Incidence and Outcomes of Heparin-Induced Thrombocytopenia in Patients Undergoing Transcatheter Aortic Valve Replacement. The American Journal Of Cardiology 2017, 120: 300-303. PMID: 28576265, DOI: 10.1016/j.amjcard.2017.04.028.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAnticoagulantsAortic Valve StenosisFemaleHeparinHospital MortalityHumansIncidenceKaplan-Meier EstimateMalePostoperative ComplicationsPrognosisRetrospective StudiesRisk FactorsSurvival RateThrombocytopeniaThromboembolismTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsVenous thrombosis/pulmonary embolismAcute kidney injuryHospital-level characteristicsHospital stayHospital mortalityKidney injuryPulmonary embolismHospital costsTranscatheter aortic valve replacementNationwide Inpatient Sample databaseOutcomes of HITPerioperative thromboembolic complicationsLonger hospital stayOutcomes of patientsAortic valve replacementHeparin-Induced ThrombocytopeniaMedian hospital costsImpact of HITTAVR groupCumulative incidenceInpatient mortalitySecondary outcomesThromboembolic complicationsValve replacementCardiac surgery