2022
Clinical, functional and prognostic implications of severe atrial dilation in secondary mitral regurgitation
Layoun H, Mentias A, Akintoye E, Matta M, Kanaan C, Daou R, Ramchand J, Burns D, Gillinov A, Bhattacharya S, Puri R, Collier P, Griffin B, Kapadia S, Harb S. Clinical, functional and prognostic implications of severe atrial dilation in secondary mitral regurgitation. Open Heart 2022, 9: e001996. PMID: 35383126, PMCID: PMC8984044, DOI: 10.1136/openhrt-2022-001996.Peer-Reviewed Original ResearchConceptsSecondary mitral regurgitationAtrial dilationMitral regurgitationPrognostic implicationsSevere left atrial dilationSevere secondary mitral regurgitationLA reservoir strainLeft atrial dilationLeft ventricle dysfunctionPoor prognostic indicatorMV interventionVentricle dysfunctionMore diabetesAdult patientsTransthoracic echocardiographyEjection fractionIndependent predictorsAtrial fibrillationReservoir strainWorse prognosisPrognostic indicatorMR severityBetter outcomesFunctional alterationsPatients
2017
Usefulness of the Mitral Regurgitation Severity Index to Assess the Severity of Chronic Mitral Regurgitation
Afonso L, Shokr M, Akintoye E, Briasoulis A, Alesh I, Alani A, Mahajan N, Veeranna V, Mostafa A, Zmily H, Telila T, Zalawadiya S. Usefulness of the Mitral Regurgitation Severity Index to Assess the Severity of Chronic Mitral Regurgitation. The American Journal Of Cardiology 2017, 120: 304-308. PMID: 28550931, DOI: 10.1016/j.amjcard.2017.04.027.Peer-Reviewed Original ResearchMeSH KeywordsBlood Flow VelocityChronic DiseaseEchocardiography, Doppler, ColorEchocardiography, TransesophagealFemaleFollow-Up StudiesHumansMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPredictive Value of TestsReproducibility of ResultsRetrospective StudiesROC CurveSeverity of Illness IndexConceptsSevere mitral regurgitationMitral regurgitationTime-velocity integralVelocity integralNonsevere mitral regurgitationChronic mitral regurgitationInter-rater reproducibilityOptimal diagnostic accuracyDerivation cohortMitral inflowValidation cohortGood inter-rater reproducibilityHigh interobserver variabilityMR severityInter-rater agreementLevel IIMean differenceDiagnostic accuracyInterobserver variabilitySeverity IndexCut pointsRegurgitationPatientsCohortSeverity