Mechanism for temporal changes in exercise capacity after Fontan palliation: Role of Doppler echocardiography
Egbe A, Khan A, Miranda W, Ammash N, Warnes C, Said S, Taggart N, Akintoye E, Veldtman G, Connolly H. Mechanism for temporal changes in exercise capacity after Fontan palliation: Role of Doppler echocardiography. American Heart Journal 2017, 196: 144-152. PMID: 29421006, DOI: 10.1016/j.ahj.2017.10.010.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultAge FactorsCohort StudiesDouble Outlet Right VentricleEchocardiography, DopplerExercise TestExercise ToleranceFollow-Up StudiesFontan ProcedureHeart Defects, CongenitalHumansMaleMichiganOxygen ConsumptionPulmonary AtresiaRetrospective StudiesTime FactorsTreatment OutcomeTricuspid AtresiaYoung AdultConceptsCardiopulmonary exercise testTransthoracic echocardiogramLV function indicesFontan palliationExercise capacityChronotropic indexFunction IndexLeft ventricleAdult Fontan patientsFontan conversion operationSystemic left ventriclePeak oxygen consumptionSerial transthoracic echocardiogramsFontan patientsFontan conversionDoppler echocardiographyRetrospective reviewDoppler hemodynamicsMean ageHemodynamic mechanismsExercise testMayo ClinicCPET dataPatientsTemporal improvementRole of diastolic function indices in the risk stratification of patients with mixed aortic valve disease
Egbe A, Khan A, Boler A, Said S, Geske J, Miranda W, Akintoye E, Connolly H, Warnes C, Oh J. Role of diastolic function indices in the risk stratification of patients with mixed aortic valve disease. European Heart Journal - Cardiovascular Imaging 2017, 19: 668-674. PMID: 28655164, DOI: 10.1093/ehjci/jex148.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAnalysis of VarianceAortic Valve InsufficiencyAortic Valve StenosisAsymptomatic DiseasesCohort StudiesConfidence IntervalsDiastoleEchocardiographyFemaleHumansMaleMiddle AgedMonitoring, PhysiologicPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentSex FactorsStroke VolumeSurvival RateUnited StatesConceptsAortic valve replacementCardiovascular adverse eventsRelative wall thicknessMixed aortic valve diseaseDiastolic function indicesAortic valve diseaseCardiac deathRisk stratificationValve diseaseFunction IndexHigh-risk patient subsetsPost-operative risk stratificationSevere left ventricular dysfunctionAtrial volume indexHeart failure hospitalizationTricuspid regurgitation velocityEarly diastolic velocityLeft ventricular dysfunctionMultivariable risk factorsAsymptomatic patientsCardiovascular morbidityFailure hospitalizationPrimary endpointSecondary endpointsVentricular dysfunction