2019
Left Ventricular Systolic Dysfunction and Cardiovascular Outcomes in Tetralogy of Fallot: Systematic Review and Meta-analysis
Egbe A, Adigun R, Anand V, West C, Montori V, Murad M, Akintoye E, Osman K, Connolly H. Left Ventricular Systolic Dysfunction and Cardiovascular Outcomes in Tetralogy of Fallot: Systematic Review and Meta-analysis. Canadian Journal Of Cardiology 2019, 35: 1784-1790. PMID: 31732195, DOI: 10.1016/j.cjca.2019.07.634.Peer-Reviewed Original ResearchConceptsCardiovascular adverse eventsLV ejection fractionLeft ventricular systolic dysfunctionLV systolic dysfunctionVentricular systolic dysfunctionSystolic dysfunctionHazard ratioLV systolic functionSudden cardiac deathNew treatment optionsClinical risk stratificationConfidence intervalsTetralogy of FallotVentricular tachycardia eventsRandom-effects modelCardiovascular outcomesAdverse eventsSystolic functionCardiac deathEjection fractionIndependent predictorsRisk stratificationPrognostic implicationsTreatment optionsTachycardia events
2017
Outcomes of cardiac pacing in adult patients after a Fontan operation
Egbe A, Huntley G, Connolly H, Ammash N, Deshmukh A, Khan A, Said S, Akintoye E, Warnes C, Kapa S. Outcomes of cardiac pacing in adult patients after a Fontan operation. American Heart Journal 2017, 194: 92-98. PMID: 29223440, DOI: 10.1016/j.ahj.2017.08.019.Peer-Reviewed Original ResearchConceptsDevice-related complicationsCardiovascular adverse eventsAdult Fontan patientsFontan patientsEndocardial leadsFontan operationPacemaker implantationRisk factorsEpicardial leadsCardiac pacingLead failureDevice-related infectionsReintervention rateAdult patientsAdverse eventsHeart transplantRetrospective reviewVenous thrombosisCardiac perforationMayo ClinicReinterventionPatientsLead recallDual chamberPacingRole of diastolic function indices in the risk stratification of patients with mixed aortic valve disease
Egbe A, Khan A, Boler A, Said S, Geske J, Miranda W, Akintoye E, Connolly H, Warnes C, Oh J. Role of diastolic function indices in the risk stratification of patients with mixed aortic valve disease. European Heart Journal - Cardiovascular Imaging 2017, 19: 668-674. PMID: 28655164, DOI: 10.1093/ehjci/jex148.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAnalysis of VarianceAortic Valve InsufficiencyAortic Valve StenosisAsymptomatic DiseasesCohort StudiesConfidence IntervalsDiastoleEchocardiographyFemaleHumansMaleMiddle AgedMonitoring, PhysiologicPredictive Value of TestsPrognosisRetrospective StudiesRisk AssessmentSex FactorsStroke VolumeSurvival RateUnited StatesConceptsAortic valve replacementCardiovascular adverse eventsRelative wall thicknessMixed aortic valve diseaseDiastolic function indicesAortic valve diseaseCardiac deathRisk stratificationValve diseaseFunction IndexHigh-risk patient subsetsPost-operative risk stratificationSevere left ventricular dysfunctionAtrial volume indexHeart failure hospitalizationTricuspid regurgitation velocityEarly diastolic velocityLeft ventricular dysfunctionMultivariable risk factorsAsymptomatic patientsCardiovascular morbidityFailure hospitalizationPrimary endpointSecondary endpointsVentricular dysfunctionCardiopulmonary exercise test in adults with prior Fontan operation: The prognostic value of serial testing
Egbe A, Driscoll D, Khan A, Said S, Akintoye E, Berganza F, Connolly H. Cardiopulmonary exercise test in adults with prior Fontan operation: The prognostic value of serial testing. International Journal Of Cardiology 2017, 235: 6-10. PMID: 28284501, DOI: 10.1016/j.ijcard.2017.02.140.Peer-Reviewed Original ResearchConceptsSerial cardiopulmonary exercise testsCardiovascular adverse eventsCardiopulmonary exercise testPercentage points/yearPoints/yearFontan operationPeak VOExercise testBaseline cardiopulmonary exercise testBaseline peak oxygen consumptionAdult Fontan patientsAdult Fontan populationPrior Fontan operationPeak oxygen consumptionPeak heart rateFontan populationFontan palliationFontan patientsPeak exerciseAdverse eventsCardiac surgeryRetrospective reviewPrognostic valueInclusion criteriaSerial testing